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Lassa fever vaccine reveals new test for immunity
A Lassa fever vaccine offers researchers a different way to test for protection, which could aid the development of more potent vaccines...
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Disease Research
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Cancer stem cells use normal genes in abnormal ways
Researchers have identified that MHC Class I-high, CDK1 high molecules may be at the heart of conditions including melanoma, pancreatic and colon cancers...
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Drug target identified in oestrogen receptors
A bridge-like structure in oestrogen has been identified by researchers at Case Western Reserve University School of Medicine as a potential drug target...
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Vaccine offers complete protection against Ebola virus
Researchers at The Wistar Institute have developed a DNA based vaccine that has offered compete protection against the Ebola virus in preclinical trials...
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Immunotherapy could cure advanced pancreatic cancer
Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...
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PIEZO2, a molecular target for neuropathic pain
Scientists at Scripps Research have identified the molecule in neurons responsible for tactile allodynia, a protein called PIEZO2...
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Early treatment could reverse autistic behaviour in tuberous sclerosis
Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
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Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
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Scientists find treatment for tumour cell population that causes tumour relapse
Researchers in Europe have developed a treatment that targets a tumour cell population responsible for therapy resistance and tumour relapse, giving optimism for patients with the most frequent form of cancer.
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Could gene mutation offer new treatment options for cardiometabolic disease?
Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
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CRISPR technique identifies Alzheimer’s biomarker
UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...
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Elrig 2018: Drug discovery using small and large molecules
The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...
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Prenatal gene editing used in treating congenital disease before birth
Researchers show the first example of a base-editing tool to treat a disease in utero in animal models...
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Biodegradable devices speed up nerve regeneration
Researchers have developed an implantable and biodegradable device to aid the regeneration of nerve after damage from accidents and sports injuries...
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Scientists create map of brain region linked to Alzheimer’s disease
Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...
