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Biological robots: a new therapeutic tool
Anthrobots derived from human tracheal cells could perform therapeutic work without initiating an immune response.
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Genome Editing
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Microbiotica: transforming medicine with microbiome magic
In this interview, Anne Neville, Director at Microbiotica, elaborates on the significance of the Microbiotica Culture Collection (MCC) and Microbiotica Reference Genome Database (MRGD), which are fundamental to the development of live biotherapeutic medicines.
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Alzheimer’s genetic variants connected with microglia function
Researchers pinpoint connections of risk variants with microglia functions that are important for Alzheimer’s disease (AD).
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Genetic scar left in the genome of bacteria
New study reveals how pneumonia cells become resistant to penicillin through evolutionary gateway.
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Proteolysis: new method developed to target cancer cells
Researchers have found that targeting chimeras with click-release proteolysis activates specific molecules that target cancer cells without harming health cells.
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ebook: Maximizing preclinical confidence in target efficacy and safety
This ebook outlines Euretos’ approach to target discovery and indication expansion. Whilst also discussing data-driven target selection.
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Multiomics approach unveils flu severity insights
Some individuals may experience more severe symptoms when infected with the same virus compared to others. The reasons behind this variability are not yet fully understood. While viral factors, such as differences in the virus strain, do play a role, they cannot account for the diverse responses observed among individuals…
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Combating malaria: new approach
Researchers are actively seeking to unravel the intricacies of gene expression regulation throughout the various stages of the P. falciparum lifecycle.
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Vaccines against parasitic disease
In Columbus, Ohio, scientists have made significant strides in developing vaccines to combat leishmaniasis, a disfiguring skin disease, through animal studies.
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Dectin-1: HIV and ageing
New study aimed to assess how Dectin-1 functions in myeloid cells among various cohorts of individuals.
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Novel based editors developed
Researchers have developed a novel based CRISPR-free base editing system named CyDENT, which enables precise base editing.
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Beyond the lab: cell & gene therapy
The launch of our new series, "Beyond the Lab," promises to deliver high-level insights commissioned exclusively by Drug Target Review magazine. Our inaugural report is an exploration of the remarkable advancements in cell and gene therapy that are revolutionising the field of drug discovery.
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Genetic variant identification: unveiling the power of STING-seq
In an exclusive interview, Dr Neville Sanjana, Associate Professor of biology at NYU and a core faculty member at the New York Genome Center, discusses the breakthrough study on STING-seq.
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Malaria unravelled: decoding the parasite’s gene expression control
Researchers from Tokyo Tech's World Research Hub Initiative conducted a study to investigate the regulation of gene expression in the apicoplast of the malaria parasite Plasmodium falciparum.
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Epigenetic editing: the next generation of genetic medicine
Dr Blythe Sather at Tune Therapeutics reveals why epigenetic editing offers benefits above and beyond those of gene editing, potentially bridging the gaps to breakthroughs in the clinic.
