Scientists have created the first lab-dish models of the cellular clock, where each 'tick' stimulates the formation of the vertebra, which uses stem cells derived from adult human tissue.
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It is said that, on average, it takes a new drug 12 years to go from research lab to patient, with many thousands of candidates discarded along the way. Can artificial intelligence (AI) help to speed things up? Sheraz Gul and Alp Sahin provide an overview of an AI approach…
Energy metabolism drives everything we do, so it is no surprise that the more we discover about these metabolic processes, the more we observe seamless integration with all core cellular functions.
The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
Researchers have identified a set of three antibodies that they suggest could become the basis for a new antiviral treatment and inform the development of new influenza vaccines.
Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay
Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…
Disruption of the MFF-VDAC1 complex could lead to a potential therapeutic target for cancer.
The worldwide market for in vitro toxicology and toxicity testing is predicted to be worth $12.7 billion by the end of the forecast period.
Innovations in synthesis technology and gene synthesis have become a powerful and valuable means of obtaining genetic material.
Monoclonal antibodies are used in a wide range of applications, such as basic research, biopharmaceutical development and in vitro diagnostics.
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
A study has predicted that the global in vitro toxicology market will rise by 8.2 percent in its forecast period.