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Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay

18 October 2019 | By

Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…