Next-Generation Sequencing (NGS)

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Valid biomarker signatures from liquid biopsies – how to standardise NGS

6 December 2016 | By Benedikt Kirchner (TUM School of Life Sciences and Ludwig-Maximilians-University Munich), Dominik Buschmann (TUM School of Life Sciences and Ludwig-Maximilians-University Munich), Michael W. Pfaffl (TUM School of Life Sciences)

The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…

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Versatile applications of next-generation sequencing in pharmaceutics

4 December 2016 | By Pushpanathan Muthuirulan (National Institutes of Health)

Next-generation sequencing (NGS) technologies hold great promise for unravelling the mysteries of biological systems, with the advent of DNA sequencing methods having greatly accelerated biomedical research, gaining broad applicability in disease diagnosis and therapeutics in recent years...

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Biocartis receives €1.4m grant to develop rapid NGS Prep Panels

31 October 2016 | By Niamh Louise Marriott, Digital Content Producer

Biocartis will use this grant, which has a duration of two years, to support the development of NGS Prep Panels (Next Generation Sequencing) for its...

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Active Motif and Swift Biosciences partner to develop advancements in epigenetics

3 October 2016 | By Niamh Louise Marriott, Digital Content Producer

Epigenetics-based research tools company Active Motif has entered into adevelopment partnership with Swift Biosciences, a next generation sequencing...

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Product Showcase: End-to-end next-generation sequencing for clinical diagnostics

20 September 2016 | By Vela Diagnostics

Fuelled by the rapid development of next-generation sequencing (NGS) technologies, it has become apparent that the technology is a key for the identification of genetic variants...

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Chemotherapy alternative: research shows Chinese medicine kills cancer cells

8 September 2016 | By Niamh Louise Marriott, Digital Content Producer

Compound kushen injection (CKI) has been used for years in Chinese clinics as an adjunct to western chemotherapy. Researchers used next generation...

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Video: Simple Western Product Overview (Wes, Sally Sue, Peggy Sue and NanoPro 1000)

6 December 2015 | By ProteinSimple

This video provides an overview of the features from the Simple Western product range by ProteinSimple, including Wes, Sally Sue, Peggy Sue or NanoPro 1000...

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Next-generation transcriptomic analysis in cancer vascular research

3 December 2015 | By Joseph Wragg (University of Birmingham), Roy Bicknell (University of Birmingham)

Over the past decade significant advances have been made in the fields of genomic and transcriptomic profiling, inspired by the advent of next-generation sequencing (NGS). Yet despite the considerable promise of these new technologies, uptake has been slow. The focus of this review is the use of next-generation transcriptomic analysis…

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App Note: Achieving 21 CFR Part 11 Compliance with the iCE3

14 October 2015 | By ProteinSimple

Rapid analysis, platform methods and easy method development make the iCE3 ideal for analyzing biologics...

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App Note: Computer-aided Assay Development for Charge Heterogeneity Analysis by iCE

13 October 2015 | By ProteinSimple

Due to protein therapeutic complexity, techniques like isoelectric focusing have become indispensable tools in evaluating biologic preparations...

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App Note: Fast, Multi-sample Particle Analysis Using MVSS 4.0

12 October 2015 | By ProteinSimple

Micro-Flow Imaging™ (MFI™) has new MVSS 4.0 software to classify particles across many biopharmaceutical samples easily and instantaneously...

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App Note: Easy Transfer of Your Traditional Western Blot to Wes

10 October 2015 | By ProteinSimple

Wes™ builds on over a decade of Simple Western development and makes running a Western even more simple...

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App Note: High Molecular Weight Protein Analysis Made Simple

9 October 2015 | By ProteinSimple

Wes now analyzes proteins up to 440 kDa with the same Simple Western speed and data quality you’ve come to enjoy...

webinar

Rapid identification and characterisation of Affimer technology

8 October 2015 | By Avacta Life Sciences

In this webinar we discuss Affimer® technology, a novel antibody mimetic and powerful antibody alternative...

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App Note: Faster and Easier Charge Heterogeneity Analysis with the iCE3

8 October 2015 | By ProteinSimple

Three major usability improvements are now available for the iCE3 system...