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Modified CRISPR gene editing tool could improve therapies
New cell experiments show more effective genetic 'cuts' that could one day become the foundation of more effective gene therapies.
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New HIV vaccine candidate design developed by researchers
A study has demonstrated a novel vaccine design in mice which could be used to immunise patients against HIV.
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Potential new target found for inflammatory disease treatment
Molecules made by immune cells to transport sodium lactate could be a target for treatment to stop the lactate build-up in chronic inflammatory disorders.
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CNS tumour aggressiveness reduced with new molecule
A microRNA inhibitor has been identified which reduced the sizes of aggressive CNS tumours and improved survival in mice.
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Transplanted stem cells used to grow functional lungs in mice
Researchers have revealed that stem cells transplanted into embryonic mice can mature into fully functional lungs, a method which could be developed to grow lungs for humans.
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Enzyme involved in cancer growth imaged for first time
A study has revealed the structure of an enzyme that promotes cancer growth by mutating RNA, which could be used in the development of cancer treatments.
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Potential antibiotic alternative discovered within bacteria
A study has revealed an enzyme in bacteria that produces a molecule which is toxic to other bacteria and shows promise as an antibiotic substitute.
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Liver-Chip used to study toxicity of drug candidates
Researchers have made a ‘Liver-Chip’ which is able to demonstrate the toxic effects of drug candidates and compounds in human patients.
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Regeneration mechanism could provide target for liver disease drugs
A newly-discovered molecular mechanism that allows damaged adult liver cells to regenerate could pave the way for drugs for chronic liver diseases.
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Novel material for regenerative medicine can control cell immune response
Researchers have created a material that can manipulate the immune response and be used as a regenerative medicine therapy.
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Optogenetics used to control diabetes without medication
Scientists in the US have successfully controlled glucose levels in diabetic mouse models without the need for medication.
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MaveDB: database to aid research into genetic causes of disease
Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.
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Mitocans partner up to provide powerful leukaemia treatment
A pioneering team of scientists from Rice University has discovered that a particular combination of chemotherapeutics, including mitocans that target mitochondria, form a powerful treatment for acute myeloid leukaemia patients.
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Key mechanism behind insulin release discovered by researchers
Researchers have identified a specific receptor that is critical for the release of insulin and provides a target for diabetes and obesity.
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Researchers identify novel signalling systems in cells
A study has revealed five new signalling processes in GPCR receptors on cells that have high therapeutic potential.