Molecules associated with NMDAR may be involved in schizophrenia
18 January 2019 | By Drug Target Review
Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia...
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Research & Development
ADM-RAMP2 system could be therapeutic target for retinal vein occlusion
17 January 2019 | By Iqra Farooq (Drug Target Review)
Researchers suggest that the retinoprotectivity of the ADM-RAMP2 system makes it an ideal therapeutic target for central retinal vein occlusion (CRVO)...
Perfect human blood vessels grown in petri dish
17 January 2019 | By Iqra Farooq (Drug Target Review)
Researchers have been able to grow perfect human blood vessels in the lab, and are now looking to conduct disease research for vascular diseases...
Neurons made from skin cells are valid when studying disease
16 January 2019 | By Iqra Farooq (Drug Target Review)
A study has found that using skin cells and transforming them into neurons is a valid approach to study neurodegenerative diseases such as Parkinson's...
Potential therapeutic target for ALS revealed
16 January 2019 | By Iqra Farooq (Drug Target Review)
Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...
Stopping inflammation using a molecular switch
15 January 2019 | By Iqra Farooq (Drug Target Review)
A component in the ubiquitin system has been described as being able to deactivate the innante immune system and could help to prevent immune conditions...
Engineered T-cells promote acceptance of organs after transplant
15 January 2019 | By Iqra Farooq (Drug Target Review)
Controlling coronin 1 in T-cells could lead to the immune system not attacking transplanted organs, but still fighting other infections...
Using the SVM method to predict enhancers from tissues and cell lines
14 January 2019 | By Iqra Farooq (Drug Target Review)
A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.
CRISPR repurposed to develop better antibiotics
14 January 2019 | By Iqra Farooq (Drug Target Review)
Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
Hidden culprit in heart failure discovered
11 January 2019 | By Drug Target Review
A study has identified that PI3K alpha could be the culprit of heart failure, as it binds to gelsolin, suppressing it and preventing it from working...
UCLA researchers correct mutation causing IPEX
11 January 2019 | By Iqra Farooq (Drug Target Review)
A stem cell therapy rectifying the FoxP3 gene has been developed to treat IPEX, and has virtually cleared symptoms of the condition in mice...
Two-antibody cocktail could treat Ebola in one dose
10 January 2019 | By Drug Target Review
A study has described a two-antibody cocktail medication that has been successful in vivo italics trials and could treat Ebola in one dose...
Whitepaper: The most important mouse in the world: the utility and applications of C57BL/6 models
10 January 2019 | By Taconic Biosciences
Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.
Stem cell study optimises bone marrow transplants
10 January 2019 | By Iqra Farooq (Drug Target Review)
A study has shown how stem cells that are transplanted act in a different way to those ordinarily present, without a transplant...
Drug sponge could minimise effects of cancer therapy
9 January 2019 | By Drug Target Review
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
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