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Novel nanoparticles improve CRISPR gene editing
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
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Gene discovered to play key role in cancer metastasis
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
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RNA editing capabilities expanded with new CRISPR platform
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
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Macrophages identified as cause of endometriotic pain
Researchers have discovered that macrophages are a key cause for pain in women with endometriosis so could be a treatment target for the condition.
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Vaccine strategy devised to boost T-cell therapy
A research team has developed a vaccine that advances antitumor T-cell population and allows the cells to invade solid tumours.
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Tauopathy-regulating protein identified
Researchers have discovered that the VPS35 molecule can be utilised in preventing neurodegenerative disorders.
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New evidence shows cytotoxic T cells can destroy targets of large mass
New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
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New target identified for vestibular diseases
Researchers have discovered a potential treatment for vestibular conditions such as dizziness in animal models.
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‘Longevity gene’ could be replicated to fight cardiovascular disease
The so-called 'longevity gene' has been included in animal models, in which it stopped atherosclerosis.
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Five latest developments for models
The use of models is a key feature of preclinical studies and in recent months there have been several new advancements in this area. This article investigates five of the latest developments.
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Natural antioxidant helps improve immune-based therapies
Scientists have discovered a way to improve immune-based treatments by modulating T cells.
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New discovery shows ability of Schwann cells to generate myelin
Research from Oregon Health & Science University could lead to new therapies to heal nervous system disorders.
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Treatment targeted at a genetic mutation relieves psychosis symptoms
A new study shows the treatment of psychosis can be targeted to a specific genetic mutation in patients with psychotic disorders.
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Researchers reverse prediabetes in mice through enzyme deactivation
A study has shown that deactivating an enzyme linked to ceramides caused obese mice to improve their metabolic health, indicating a drug target.
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