Paving the path towards precision medicine
21 March 2019 | By Drug Target Review
A method to view the immune cell 'landscape' of bowel cancer tumours could pave the way towards more individualised medicine and treatment...
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Research & Development
Fast molecular interaction screening for all your projects
21 March 2019 | By NanoTemper Technologies
Current technologies that measure molecular interactions for drug discovery slow down and complicate screening. Dianthus is the answer to the demands for fast, non-stop, highly sensitive hit identification, hit validation and lead optimisation.
Epigenetic protein could be new therapeutic target in acute myeloid leukemia
19 March 2019 | By Drug Target Review
The epigenetic protein, EZH2, was found to delay the development of acute myeloid leukemia (AML) but also switches sides to maintain tumour growth...
Ticagrelor reversal agent provides immediate and sustained relief
18 March 2019 | By Drug Target Review
A reversal agent that sustains immediate relief from the side effects of ticagrelor stopping major bleeding, such as gastrointestinal hemorrhage...
USP15 enzyme could have role in the future treatment of cancer
15 March 2019 | By Drug Target Review
Researchers have found that the enzyme USP15 could potentially lead to new therapies for both breast and pancreatic cancer...
Machine-learning model to analyse protein sequences
14 March 2019 | By Iqra Farooq (Drug Target Review)
A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
Optical imaging technique to detect tiny tumours
8 March 2019 | By Iqra Farooq (Drug Target Review)
A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
Potential EBV-associated cancer treatment in small molecule inhibitors
7 March 2019 | By Iqra Farooq (Drug Target Review)
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
Salamander gene partnerships could help spinal cord regeneration
6 March 2019 | By Iqra Farooq (Drug Target Review)
Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori
5 March 2019 | By Iqra Farooq (Drug Target Review)
Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
Genomics to match treatments to pancreatic cancer patients
4 March 2019 | By Nic Losardo (Drug Target Review)
Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
Protein marker in response to brain cancer therapy
1 March 2019 | By Fraser Owen (Drug Target Review)
An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
Genetic study confirms that numerous genes contribute to Tourette’s syndrome
1 March 2019 | By Iqra Farooq (Drug Target Review)
A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
Colon cancer pathway discovery could lead to targeted therapies
28 February 2019 | By Nic Losardo (Drug Target Review)
Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer...
Counteracting T-cell exhaustion in CAR-T cancer therapies
27 February 2019 | By Iqra Farooq (Drug Target Review)
Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
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