Defective damage repair to DNA results in chromosome chaos
13 November 2018 | By Drug Target Review
German researchers have shown how defective damage repair to DNA results in chromothripsis - clustered chromosomal rearrangements...
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Research & Development
Vaccinia virus hijacks cellular movements to spread
13 November 2018 | By Iqra Farooq (Drug Target Review)
To spread throughout the body, the vaccinia virus mimics the infected cells' own proteins enabling the cell to move around and spread...
CRISPR used to prevent cancers tied to EBV and KSHV
13 November 2018 | By Drug Target Review
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...
RIP1 kinase as a therapeutic target for pancreatic cancer
12 November 2018 | By Iqra Farooq (Drug Target Review)
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
Swarm of exosomes protect against inhaled bacteria
12 November 2018 | By Iqra Farooq (Drug Target Review)
A swarm of billions of exosomes armed with proteins has been shown to assist in the fight against bacteria inhaled through the nose...
Mouse model for diabetic kidney disease suggests role for immune and inflammatory pathways
12 November 2018 | By Drug Target Review
Scientists have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy...
Magnetically controlled thrombolytic passed preclinical trials
9 November 2018 | By Iqra Farooq (Drug Target Review)
Researchers from ITMO University have used nanoparticles and magnetic waves to localise drug delivery in animal models, resulting in no side effects...
Drug repurposing using off patent drugs as antifungals
9 November 2018 | By Iqra Farooq (Drug Target Review)
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
Sensory neurons can be used to discover therapies for ALS
9 November 2018 | By Drug Target Review
New approach for testing for ALS may be useful to reverse debilitating disease...
Disrupting quinolones to prevent antibiotic resistance
8 November 2018 | By Iqra Farooq (Drug Target Review)
Disrupting the communication between bacteria and quinolone signalling can inhibit the the production of toxins and virulence factors...
Anti-inflammatory bacterial protein discovered in zebrafish
8 November 2018 | By Iqra Farooq (Drug Target Review)
An anti-inflammatory bacterial protein discovered in zebrafish could lead to the discovery of anti-inflammatory proteins within humans...
Gene responsible for hair loss discovered
7 November 2018 | By Iqra Farooq (Drug Target Review)
The gene responsible for hair loss caused by the hypotrichosis simplex has been discovered by researchers at the University of Bonn...
Making old antibiotics work better using r8
7 November 2018 | By Iqra Farooq (Drug Target Review)
A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...
P2K system could resolve bottlenecks in drug research
7 November 2018 | By Drug Target Review
Researchers have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests...
Harmonising drug-target binding data analytics on a single platform
6 November 2018 | By PerkinElmer
This webinar outlined the fundamentals of a design process where an experimental analytics data workflow is being integrated into a more seamlessly interactive platform...
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