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Genes responsible for gender differences in tumours identified
A new study has identified possible regulators that determine differences in cancer tumours between genders.
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Application note: Oxidative Stress Measurements Made Easy
The advantages of detection of oxidative stress by high content analysis.
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Understanding Cell Death by High Content Analysis
Cell death is a process that occurs as both a part of normal tissue homeostasis and can be aberrantly regulated in some disease states, specifically cancer.
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Genes linked to Alzheimer’s risk have been identified
Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.
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Single enzyme provides target for new sepsis drugs
Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
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Therapeutic target for Kennedy’s disease and prostate cancer proposed
A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.
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Potential treatment target identified for Crohn’s disease
Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.
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New drug could be used for targeted cancer therapies
A new drug called IP1867B, which could be used for future treatments of brain tumours, is being examined.
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Researchers grow genetically engineered mini livers to study disease
The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.
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Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
webinar
Measuring the affinity of challenging protein targets
31 July 2019 | By Fluidic Analytics
Join us as we discuss the latest data from the literature and application studies where diffusional sizing (MDS) is used to assess a variety of protein interactions – even of difficult targets.
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Application note: Monitoring Aggregation of Antibody-Drug Conjugates
30 July 2019 | By
Prediction of Aggregation Propensity and Monitoring of Aggregation of Antibody-Drug Conjugates (ADC).
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New evidence shows cytotoxic T cells can destroy targets of large mass
New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
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New target identified for vestibular diseases
Researchers have discovered a potential treatment for vestibular conditions such as dizziness in animal models.
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Treatment targeted at a genetic mutation relieves psychosis symptoms
A new study shows the treatment of psychosis can be targeted to a specific genetic mutation in patients with psychotic disorders.