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Method developed for quicker and simpler production of lipidated proteins
A simple and direct method of introducing lipids into protein has been developed using palladium as a catalyst.
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CRISPR RNA-cutting enzyme programmed to kill viruses in human cells
Researchers have developed CRISPR-Cas13 enzyme-based technology that can be programmed to both detect and destroy RNA-based viruses in human cells.
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‘Tricking’ bacteria could lead to more effective antibiotics
A technique to 'trick' bacteria into revealing pores in their cell walls has been developed and targeting these could make antibiotics more effective.
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Bacterial strain identified that determines fate for rotavirus sufferers
Scientists in the US have identified a particular bacterial strain, Segmented filamentous bacteria (SFB), that can prevent and cure rotavirus in mice.
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New therapeutic target identified for pulmonary fibrosis
A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
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Best targets for immunotherapy identified by new model
A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
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Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
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Anticancer activity delivered by targeting mitochondrial cell regulator
Disruption of the MFF-VDAC1 complex could lead to a potential therapeutic target for cancer.
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Protein responsible for muscle degeneration identified
A study has demonstrated that a certain protein is critical in the decline of muscle regeneration, with the researchers also showing how to inhibit this process in mice.
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Weapon bacteria could be copied to create new forms of antibiotics
New antibiotics could be designed by discovering the mechanism a weapon bacteria uses to vanquish their competitors.
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Nipah and Hendra virus attack neutralised by potent antibody
Researchers have shown that a monoclonal antibody prevents viruses from fusing with cell membranes to gain entry.
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High-throughput screening used to discover new class of antibiotics
Researchers have used a high-throughput screening method to test over 125,000 molecules and identify a new class of antibiotics.
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Scientists discover unique imaging technique to view synapse proteins
Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
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Application note: Automated imaging of cell viability
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
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A biosynthetic pathway to identify new drug candidates
A new process for identifying and biosynthesising drug candidates has been discovered by researchers at the Carl R Woese Institute for Genomic Biology.