A new gene therapy that introduced SynCav1 to the brains of Alzheimer's mouse models was shown to preserve neuronal and synaptic plasticity.
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Four hepatitis C drugs have demonstrated promise as boosters to increase the efficacy of remdesivir against SARS-CoV-2 by as much as tenfold.
Scientists have developed a drug called STM2457 which inhibits a key enzyme involved in acute myeloid leukaemia.
Oral doses of a new drug named CA administered to mouse models led to improvements in Alzheimer's disease, including memory.
Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
Dr James Woody discusses off-patent indications for anti-TNF to address unmet patient needs in pain, inflammation and beyond.
The drug MK-4482 decreased viral levels in the lungs of hamsters treated for SARS-CoV-2 infection, researchers have shown.
Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.
In vitro evaluation of hepatic function using a primary human hepatocyte 3D spheroid culture system
Hypoxia measurements in live and fixed cells using fluorescence microscopy and high-content imaging
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
High-throughput fluorescence imaging and analysis of spheroids - tips, tricks, and tools to efficiently grow, stain, image, and analyze 3D cell cultures
The advantages of detection of oxidative stress by high content analysis.
Cell death is a process that occurs as both a part of normal tissue homeostasis and can be aberrantly regulated in some disease states, specifically cancer.