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Scientists have developed an organ-on-a-chip platform that replicates age-related immune decline, offering a long-missing tool for testing cancer vaccines in older adults.
Shift Bioscience has announced new aging research, highlighting the discovery of SB000. This novel single-gene target reverses cellular aging without activating dangerous pluripotency pathways.
Download our latest report to discover how stem cell research is revolutionising treatments for chronic diseases, cancer and regenerative medicine.
Disrupting F-actin in aged brains restored brain autophagy to youthful levels and reversed some cellular markers of brain ageing.
Targeting the epigenetic states of specific retroelements in the human genome could mitigate the biological effects of ageing.
In this Q&A, Dr Ronald DePinho of MD Anderson elucidates their preclinical proof-of-concept that adjusting TERT levels could be a viable therapeutic approach for mitigating age-related diseases, such as cancer, heart disease and Alzheimer’s.
Researchers highlight the need for considering biomarkers alongside other health outcomes, as well as the need for omic data standardisation.
Contrary to popular belief, ageing is not caused by just random wear and tear of our bodies over time but is instead caused by a discrete set of biological mechanisms that we now better understand and can target with therapies. Life Biosciences are specifically focused on restoring and prolonging one’s…
Boosting the body’s anti-viral immune response could restore tissue balance and eliminate ageing cells that contribute to age-related diseases.
A new study provides the possibility to evaluate the capacity of telomerase-positive human urine-derived stem cells to become a wide variety of other cell types.
Genflow have announced a scientific research collaboration with the University of Rochester’s Aging Research Center. Together, they will study the ageing process in liver tissue.
New research by the Salk Institute has shown cellular rejuvenation therapy safely reverses signs of ageing in mice.
Researchers have found that genes in small organisms, known to extend lifespan, could also impact ageing in humans.
The database could save substantial resources for those wanting to do pre-clinical studies of interventions for age-related diseases, said scientists.
New research reveals that age-related declines in cellular function and proliferation occur in multiple stages, accompanied by different inflammatory responses.
