A novel synthetic “switch” has been developed that could hold the key to revolutionary smart insulin therapy for diabetic patients.
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A small molecule found in a cell-based ultra-high-throughput screening campaign was shown to treat diabetes in cells and mice.
Despite the promise of gene therapies, significant challenges have emerged in the field. Dr Carsten Brunn discusses the current obstacles and opportunities when developing gene therapies.
Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.
The global cell-based assays market is expected to grow due to increasing investments into cell-based research and a rise in chronic diseases.
Dr Brittany Busse discusses why COVID-19 can influence the onset of diabetes and how this could shape the development of therapeutics.
A team has developed a lotus-root-shaped construct to deliver iPSC-derived pancreatic beta-cells to patients with type I diabetes mellitus.
A novel artificial intelligence (AI) technique called ProteinGAN has shown success at studying well known proteins to develop new ones.
A year on from discovering COVID-19 we are starting to understand why some people suffer more severely after infection. Sadya Arnett discusses recent research into the interconnection between host inflammation and SARS-CoV-2.
A monoclonal antibody given to mice reversed type 1 diabetes by suppressing the actions of glucagon, a study has shown.
A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.
Jim Shanahan from SynDevRx explains why metabo-oncology treatment modalities could be the answer to a rise in metabolic disorders and cancers.
In a new study, inhibitors of the GLS1 enzyme caused the death of senescent cells and relieved the symptoms of various age-related diseases in mice.