The NPGPx protein is active in foetuses, but largely dormant and absent in diabetic adults.
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Trinity College Dublin has developed a new technique that accurately determines the state of macrophages.
Drug-initiated activity metabolomics screening discovers the metabolite myristoylglycine, that converts white fat cells to brown fat cells.
Researchers have discovered a protein, Ait1, that is responsible for controlling cell growth in yeasts. Since humans and yeasts have remarkably similar cellular mechanisms, teasing out the differences presents drug developers with new target.
After initially serving as a proving ground for integrating forward engineering principles into living cells, synthetic biology is making waves across diverse therapeutic areas. In this article, Dr Dan Mandell, Co-Founder and CEO of GRO Biosciences, explains how the field is reshaping our understanding of the limits of cell- and molecular-based medicines.
A report has shown that the immuno-oncology drug discovery outsourcing market is set to be worth $2563 million by 2030.
Scientists at the Endocrine Society have found extracellular vesicles may offer new insights into treating endocrine disorders.
A new study by University of Texas Health Science Center at San Antonio has found that boosting liver mRNAs in obese mice reduces appetite and body weight.
Researchers from the University of Pennsylvania may have discovered how to eliminate the risk of weight gain from certain diabetes medications by uncovering the difference between two varieties of a protein.
A recent pre-clinical study from Washington University School of Medicine showed that a new class of compounds can potentially improve multiple aspects of metabolic syndrome, including diabetes.
A new study has identified harmful cellular pathways that prevent insulin production, presenting a drug target for diabetes.
Scientists have developed a multi-organoid system from stem cells that can replicate the liver-islet axis in type 2 diabetes.
Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.
Here, we round up some of the key takeaways from the expert panel discussions at the Cell & Gene Therapy Advancements Online Summit.
US researchers have identified new biomarkers that can detect early changes in the eye that can lead to diabetes-related blindness.