Researchers have implicated long non-coding RNAs in tumour progression and suggest they may be potential drug targets for cancers with p53 mutations.
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Researchers demonstrate that their novel small molecule, which activates the STING protein, supresses tumour growth and metastasis in a murine model of aggressive melanoma.
A new study conducted in Israel suggests that T cells’ ability to destroy skin cancer increases in the absence of T-cell regulators called SLAMF6.
Researchers have revealed that the WDR74 protein plays a key role in lung cancer and melanoma, including metastasis, indicating it may be a potential drug target.
An innovative new vaccine technique, which sensitises the immune system to the genetic signature of APOBEC mutations (often found in cancers), increases the efficacy of immunotherapies.
A study of published papers has revealed the importance of research into how the microbiome affects the development of melanoma.
A study has shown that long non-coding RNA called DIRC3 can block melanoma growth and could be used to identify new targets for skin cancer therapies.
Upregulation of the c-Cbl gene causes degradation of the immune checkpoint protein PD-1 and may provide a possible new avenue for cancer therapies, according to researchers.
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
A study has found that removing a particular kind of macrophage enables the immune system to attack tumours, providing a potential drug target.
A protein discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
Researchers have revealed a key inflammation mechanism that contributes to melanoma brain metastasis and could be a therapeutic target.
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.