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This application note demonstrates the feasibility of combining the Thermo Scientific™ Varioskan™ LUX multimode reader and Invitrogen™ EVOS™ FL Cell Imaging System for the fluorescence-based quantification and imaging of complex biological systems, without requiring separate assay optimisation...
Umeå researchers have created datasets that map the three-dimensional distribution and volume of the insulin-producing cells in the pancreas.
Drug developers sometimes think of imaging as an emerging discipline. But John Waterton, Paul Hockings, Juliana Maynard and Caleb Roberts explain how imaging biomarkers are transforming drug development. Francesco Gatto and Jens Nielsen, from the Chalmers University of Technology in Sweden, discuss moving towards systems biomarkers for cancer diagnosis...
Included in this issue: Importance of building patient trust; Vaccines & Immunology; Oncology; Assays; Biomarkers; and Antibodies...
Drug developers sometimes think of imaging as an emerging discipline, full of esoteric technologies of marginal relevance to real-world clinical drug development. In fact, the opposite is true: imaging measurements (imaging biomarkers) are used daily in drug development and in personalised medicine. They assess target engagement and receptor occupancy in…
Two-dimensional monolayer cell proliferation assays for cancer drug discovery have enabled large-scale screens. But they represent a simplified view of oncogenes or tumour suppressor genes as the genetic drivers of cancer cell proliferation.
Researchers at the University of Rochester Medical Centre have developed a new imaging technique to better assess eye health and potential disease.
21 December 2016 | By DiscoverX Corporation
The movement of proteins between cellular compartments is essential for their specific biological role and the function of the cell...
A new study has confirmed the anti-diabetic properties of the purslane herb extract Portulaca oleracea L.
3 November 2016 | By Niamh Louise Marriott, Digital Content Producer
A recent investment of €3.3 million will allow researchers to improve the detail of medical imaging ten times over, which will allow for tumour scanning...
13 October 2016 | By Charles River Laboratories
Enhances Charles River’s early-stage capabilities in bioanalytical services...
Integrating the S3e™ Cell Sorter into sample preparation upstream of the QX200™ Droplet Digital System provided details about cell subpopulations that would have been undetectable in heterogeneous populations...
28 September 2016 | By Niamh Louise Marriott, Digital Content Producer
During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...
