news
Celyad awarded US patent covering allogeneic human primary T-Cells
26 October 2015 | By Victoria White
The US 9,181,527 Celyad Allogeneic Patent significantly strengthens Celyad’s patent portfolio in the CAR T-Cell field...
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Stem Cells
news
Disease recreated in mini-kidney organoids in the lab
23 October 2015 | By Victoria White
The work paves the way for personalised drug discovery for kidney disease...
news
iPSC technology helps characterise healthy and diseased neurons
23 October 2015 | By Victoria White
Using iPSC technology, researchers created 16 different cells lines, some using cells from healthy humans and others using cells from people with ALS or spinal muscular atrophy...
webinar
Key Ligand-Gated Ion Channels in CNS Drug Discovery
15 October 2015 | By Charles River
Ligand-gated ion channels including, GABAA, NMDA, and nicotinic acetylcholine receptors, are important therapeutic targets in neurological disorders...
news
Researchers develop animal-free renal screening platform
13 October 2015 | By Victoria White
Researchers have developed the first animal-free screening platforms capable of predicting the toxic effects of compounds on the human kidney accurately...
news
Asterias collaborates with Cell Therapy Catapult to scale production of AST-VAC2
13 October 2015 | By Victoria White
AST-VAC2 is an immunotherapy product that contains mature dendritic cells derived from pluripotent stem cells...
news
Researchers turn stem cells into mini-kidneys
8 October 2015 | By Victoria White
The breakthrough could allow the use of mini-organs to screen drugs either for the treatment of kidney disease or to find out if a new drug is likely to injure the kidney...
news
Nektar submits IND for NKTR-214 to treat solid tumours
8 October 2015 | By Victoria White
NKTR-214 is a CD122-biased immune-stimulatory cytokine that is designed to stimulate the expansion and maintenance of CD8-positive effector T-cells...
webinar
Phenotypic Screening in Drug Discovery
28 September 2015 | By Charles River
This webinar describes an approach to phenotypic discovery through bioprofiling in human primary cell-based assays across several disease areas (case study)...
news
TSRI awarded $6 million to develop HIV/AIDS vaccine, eCD4-lg
25 September 2015 | By Victoria White
When eCD4-lg was tested in animal models, the results were so powerful and effective that they suggested the compound’s potential to serve the role of an alternative HIV/AIDS vaccine...
article
Ion channels: Small molecules versus biologics – the quest for the ideal Nav1.7 inhibitor
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…
news
Auspherix and Domainex expand antibiotics partnership
15 September 2015 | By
Since initiating the project in 2014, significant progress has been made towards the invention of new compounds with activity against both gram-positive and gram-negative bacteria...
webinar
Immunology Screening on the iQue Screener
14 September 2015 | By IntelliCyt
Immunology Screening on the iQue Screener: Assays for Immune-Modulators and Immunotherapy...
news
Major advance towards long-lasting universal influenza vaccine
25 August 2015 | By Victoria White
Scientists from The Scripps Research Institute (TSRI) and Janssen have found a way to induce antibodies to fight a wide range of influenza subtypes...
news
Scientists replicate newt cell regeneration with human cells
21 August 2015 | By Victoria White
Scientists have adapted the astonishing capacity of newts to regenerate tissue to rejuvenate cells from older people with osteoarthritis...
