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Ann & Robert H. Lurie Children's Hospital of Chicago

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Nanoparticle delivery of CRISPR enables genome editing of vascular endothelium

6 January 2022 | By Victoria Rees (Drug Target Review)

According to researchers, a new method to deliver CRISPR-Cas9 to vascular endothelial cells could be used to treat many diseases, including COVID-19.

Healthy nerve next to nerve with damaged myelin, indicating multiple sclerosis

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Mechanism discovery provides new model for studying multiple sclerosis

23 September 2021 | By Anna Begley (Drug Target Review)

The over-expression of a growth factor receptor resulted in hypomyelination, leading to diseases such as multiple sclerosis in mouse models.

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New nanotherapy could potential treat Crohn’s disease in children

18 February 2021 | By Victoria Rees (Drug Target Review)

A novel nanotherapy can decrease intestinal inflammation and shrink lesions in rodent models of Crohn's disease, a study has shown.

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Study shows that CRISPR-Cas9 gene editing has a low risk of mistakes

4 December 2019 | By Rachael Harper (Drug Target Review)

A study has shown that unintended mutations from gene editing with CRISPR-Cas9 are rare in zebrafish, providing reassurance that this technology is a valid tool with great promise for the treatment of genetic disorders.

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Ann & Robert H. Lurie Children's Hospital of Chicago

Nanoparticle delivery of CRISPR enables genome editing of vascular endothelium

Mechanism discovery provides new model for studying multiple sclerosis

New nanotherapy could potential treat Crohn’s disease in children

Study shows that CRISPR-Cas9 gene editing has a low risk of mistakes