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Improving ovarian cancer outcomes with artificial intelligence
Researchers have developed an AI based model that is 80 percent accurate in predicting the therapy outcome of high-grade ovarian cancer.
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University of Cambridge
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New understanding of early breast cancer development
Mammary organoid cultures show the effects of BRCA2 mutations on breast tissue cells, increasing the likelihood of early, targeted treatment.
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Vascular cells essential in forming long-term memories
New research reveals capillary cells and neurons work together to ensure memory formation and storage.
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Dynamic molecular aggregates within cells
Researchers from the University of Freiburg and the University of Cambridge have observed live cell formation of membraneless molecular aggregates, uncovering the interplay between biological mechanisms and physical force.
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Scientists generate a mouse embryo model that develops neural tubes
The new mouse embryo model system promises to spur research into developmental health and disease.
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Llama nanobodies could prevent a deadly post-transplantation infection
A new study has shown that nanobodies derived from llamas could have the potential to destroy human cytomegalovirus.
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ELRIG: New modalities in pharmacology and drug discovery
Drug Target Review’s Ria Kakkad recently visited ELRIG and the British Pharmacological Society’s conference on New Modalities in Pharmacology and Drug Discovery which took place in London, UK. This article shares some of the key takeaways from the event.
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Whole genome sequencing in cancer research
A recent whole genome sequencing study has revealed hidden insights into the causes of cancer. In an exclusive article, Dr Andrea Degasperi from the Early Cancer Institute at the University of Cambridge, UK spoke to Drug Target Review's Ria Kakkad about the study's implications and the future of whole genome sequencing.
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Ultra-powerful brain scanners offer hope for treating cognitive symptoms in Parkinson’s disease
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
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Immune cell populations have been mapped to provide new insights into how the immune system works
Two new papers from the Human Cell Atlas shed new light on the types and traits of immune cells that can be found in the human body, from developmental stages to adulthood.
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Whole genome sequencing study reveals hidden insights about the causes of cancer
DNA analysis of thousands of tumours has uncovered insights about the causes of cancer, with genetic mutations providing a personal history of the damage and repair processes each patient has been through.
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Defective mitochondria could be repaired using gene-editing techniques, study finds
Researchers have shown that it could be possible to modify the mitochondrial genome, paving the way for new treatments for incurable mitochondrial diseases.
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Inhibiting METTL3 enzyme combats acute myeloid leukaemia in mice
Scientists have developed a drug called STM2457 which inhibits a key enzyme involved in acute myeloid leukaemia.
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Bile duct organoids could be used as cell therapy for regenerative medicine
For the first time, scientists have grown bile duct organoids that could repair damaged ducts and livers as a new cell therapy.
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Researchers discover how SARS-CoV-2 infects and replicates in host cells
A team has revealed how SARS-CoV-2 infects cells, suggesting that targeting its RNA with drugs would stop the virus replicating.