news
Powerful computer modelling approach developed to simulate cells
A study has proposed a new technique for modelling living cells at atomic resolution, which could be used to research human health.
List view / Grid view
Bioinformatics
news
Artificial intelligence model finds potential drug molecules a thousand times faster
A geometric deep-learning model is faster and more accurate than state-of-the-art computational models, reducing the chances and costs of drug trial failures.
news
New scientist at Rockefeller University plans to unlock vast chemical spaces for drug discovery using algorithms
Jiankun Lyu hopes to use algorithms to find improved drugs by screening chemicals that may look different to a protein’s known ligands but work in a similar way.
news
AI-based screening method could boost speed of new drug discovery
Using an AI algorithm that models drug and target protein interactions, researchers achieved up to 97 percent accuracy in identifying promising drug candidates.
news
New approach to brain imaging leaves skulls intact in mice
The researchers created a chronic skull optical clearing window where they no longer needed to remove any piece of the skull.
news
Researchers develop a small molecule that makes immunotherapy available to all cancer patients
Scientists have identified and synthesised a small molecule that could be a more accessible and affective alternative to an antibody that treats a wide range of cancers.
news
First captured image of antigen-bound T-cell receptor at near-atomic resolution
Using cryo-electron microscopy, researchers have captured the structure of a membrane-bound T-cell receptor complex with bound antigen.
news
Unravelling cell biology through artificial intelligence
The AI algorithm was able to predict the presence and the location of nuclei in more than 8,000 cells.
news
New machine learning technique to accelerate the process of drug screening
Researchers have developed a machine learning method to quantitatively analyse and compare microscopy images of proteins.
news
Sound and electrical body stimulation could treat chronic pain
12 August 2022 | By
A new technique could relieve pain for individuals with various chronic and neurological conditions.
news
Using optogenetics to restore cell function
In a new study, researchers have found that light can be used to naturally balance a cell’s mitochondria.
news
Study reveals potential therapeutic targets for pancreatic cancer
Researchers analysed the expression of long non-coding RNAs in samples from patients and tumour cell lines, identifying a group of genes with augmented expression in pancreatic cancer.
news
A mathematical algorithm to network complex drug interactions
Researchers used mice to develop a mathematical algorithm of a heart attack.
article
Spatial biology is the next life science revolution
Dr Richard Goodwin, Head of Imaging & AI, Clinical Pharmacology & Safety Sciences at AstraZeneca, explores the latest innovation in early therapeutic development – spatial biology.
article
Drug Target Review Imaging ebook
In this section, Dr Peter O’Toole, University of York, examines innovation in the field of microscopy for drug discovery and development research, while in an exclusive Q&A, Dr Michael Grange, Rosalind Franklin Institute, discusses the advantages of utilising cryo-electron tomography imaging.
