whitepaper
ebook: Maximizing preclinical confidence in target efficacy and safety
This ebook outlines Euretos’ approach to target discovery and indication expansion. Whilst also discussing data-driven target selection.
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Cell Cultures
news
Newly identified cell type uncovered in the thymus
Microfold cells (M cells) are primarily known for their role in the intestinal epithelium. However, the researchers discovered similar cells in the thymus.
whitepaper
Beyond the lab: cell & gene therapy
The launch of our new series, "Beyond the Lab," promises to deliver high-level insights commissioned exclusively by Drug Target Review magazine. Our inaugural report is an exploration of the remarkable advancements in cell and gene therapy that are revolutionising the field of drug discovery.
webinar
Bridging the gap: using organ-on-a-chip as an experimental tool to develop (cost) effective therapeutics
25 July 2023 | By CN Bio
The webinar will explore primary concerns in drug discovery development and why drugs fail.
whitepaper
Case study: Mitochondrial toxicity in drug discovery and development
The Agilent Seahorse XF assay platform has opened new avenues for examining mitochondrial health in a timely and effective manner.
article
Exploring alternatives to animal testing in drug discovery
The use of animal studies in drug development has become a growing ethical concern, particularly given the high failure rate of clinical trials, which can reach up to 90 percent. This article highlights non-animal models that could expedite the drug delivery process from bench to bedside.
article
Key considerations before commencing cell line development
Cell line development (CLD) is a critical, early step when entering the development phase of a biotherapeutic. Access to specialist skills and experience, either in-house or remotely, and to multiple technologies and equipment can prove invaluable for the timely and successful completion of this stage. Here, Dr Alison Porter addresses…
news
Novel hydrogel brings hope for infertility and fertility challenges
South Korean researchers have developed a hydrogel using a uterus-derived decellularised extracellular matrix, bringing hope for those challenged with infertility.
article
Women in STEM with Dr Jo Brewer
Come and join us for our monthly series highlighting Women in STEM. We are excited to present the latest edition for June, featuring an exclusive interview with Dr Jo Brewer, Chief Scientific Officer at Adaptimmune. With a remarkable 15-years of experience in cell therapy, Jo's passion for cells has been…
webinar
Cardiac and vascular safety liabilities using totality of evidence approach
27 June 2023 | By Eurofins Discovery
US-FDA recommend integration of both preclinical (S7B) and clinical (E14) data to improve risk assessment, reduce reliance on TQT clinical studies, streamlined drug-development, simplified decision-making processes, effective risk-communication.
news
Drug helps reduce bacterial antibiotic resistance
US researchers uncover a new drug that reduces the ability of bacteria to develop antibiotic resistance, prolonging the antibiotic effectiveness.
news
3D bioprinting artificial organs could become quicker and easier
Novel 3D bioprinting process could save thousands of lives by streamlining the creation of tissue-compatible artificially engineered organs.
webinar
Innovations in organoid modelling for disease modelling and cell therapy
14 June 2023 | By Sartorius
Watch our virtual panel, where you'll uncover the game-changing advantages of organoids over traditional 2D cultures. Our experts will explore the immense potential of organoids in oncology and immuno-oncology research.
whitepaper
Application note: Simplify the qualification of your GMP proteins
A fast, easy, and streamlined method for characterizing cytokine identity and purity with automated capillary electrophoresis (icIEF and CE-SDS).
video
Video: Using luciferase reporter cell lines for HTS readouts
This video reviews the uses and advantages of reporter cell lines in the context of cellular research and drug discovery.