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Cytokines

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Cytokine molecules unearth development of progressive MS

19 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have uncovered two closely related cytokines molecules involved in cell communication that explain why some people develop progressive MS...

whitepaper

Application note: Application of MultiCyt QBeads for high throughput cytokine profiling in human peripheral blood mononuclear cells

18 September 2017 | By Kim Luu (IntelliCyt Corporation), Robbie Narang (IntelliCyt Corporation), Zhaoping Liu (IntelliCyt Corporation)

In this application note IntelliCyt Corporation report on the development and validation of their family of MultiCyt QBeads for the detection of cytokines in a high-throughput screening application on the iQue Screener...

news

IL-34: a new target to tackle chemo-resistant cancer cells

3 October 2016 | By Niamh Louise Marriott, Digital Content Producer

Researchers found that A549-DR was resistant to the chemotherapeutic drug when transplanted in mice, while A549-DR with depleted IL-34 became sensitive...

article

Immune checkpoint inhibitors: targets on the horizon

19 April 2015 | By Kerstin Papenfuss (MRC Technology)

Immune checkpoint inhibitory antibodies have provided a great conceptual change in the field of immune-oncology. Rather than targeting the tumour directly, these novel drugs are aimed at preventing the interactions between the tumour and the immune system, which the cancer exploits to evade immune recognition...

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