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Gene therapy approach shows promise in treating ALS
In rodent models of ALS, the introduced neuroprotective protein slowed disease progression and increased life span.
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Disease Research
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Using optogenetics to restore cell function
In a new study, researchers have found that light can be used to naturally balance a cell’s mitochondria.
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An EGFRvIII-targeted immune-based therapy could potentially treat glioblastoma
A T-cell bispecific antibody shows potent anti-tumour activity in preclinical models of epidermal growth factor receptor variant III (EGFRvIII) mutant glioblastoma.
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Scientists create a nanobody that could treat Parkinson’s disease
Researchers have developed a nanobody that can penetrate the tough exterior of brain cells and untangle misshapen proteins that lead to Parkinson’s disease.
whitepaper
Whitepaper: High throughput, multi-parametric analysis
This whitepaper overviews how high throughput, multi-parametric analysis accelerates antibody discovery workflows.
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Progress towards a stem cell-based therapy for blindness
Scientists are developing an effective stem cell-based therapy to regenerate photoreceptors cells and restore sight in people with blindness.
whitepaper
Application note: LlaMAbody™ camelid antibodies flyer
Single-domain antibodies (sdAb) are small, stable antibodies derived from camelids with a single monomeric variable domain.
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Study reveals how molecular motor proteins are involved in malaria transmission
Scientists have made a breakthrough in how malaria parasites divide and transmit the disease, a major step forward in preventing one of the biggest killer infections in the world.
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Study reveals potential therapeutic targets for pancreatic cancer
Researchers analysed the expression of long non-coding RNAs in samples from patients and tumour cell lines, identifying a group of genes with augmented expression in pancreatic cancer.
webinar
How 3D biology is shaping the future of drug discovery
27 July 2022 | By Molecular Devices & HeartBeat.bio
Watch this virtual panel discussion to identify ways to overcome common challenges in 3D biology research, regardless of where you are in your journey.
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Potential target for type 1 diabetes treatment
Researchers have discovered a new pathway to the regeneration of insulin in pancreatic stem cells, findings that could move towards new therapies for type 1 and type 2 diabetes.
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Takeda enters agreement with F-star Therapeutics to license bispecific antibody
F-star Therapeutics has announced a licence agreement with Takeda for a novel next-generation immuno-oncology bispecific antibody.
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Monkeypox an international health emergency, WHO declares
The World Health Organization has declared monkeypox a Public Health Emergency of International Concern, the highest level of alert.
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Researchers create weakened version of SARS-CoV-2 that does not cause illness or death
Scientists have received approval to work with a weakened, non-harmful version of SARS-CoV-2 in biosafety level 2 laboratories, which makes it more efficient to study the virus, and to identify new treatments.
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The potential of Ayurvedic medicine
In a recent study, scientists have highlighted the possible use of South Asian medicine, specifically, Ayurvedic medicine, to treat type 2 diabetes. In this article, Drug Target Review dives into the study’s implications and what it means for the western world of drug discovery.
