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Drug Discovery Processes
Declines in plasticity reveal promising targets for Alzheimer’s disease
Brain changes linked to memory loss may provide a new focus for exploring ways to treat or prevent dementia...
Key psychiatric drug target comes into focus
Researchers have reported a major step forward towards designing more powerful psychiatric drugs with fewer side effects...
Scientists develop broad-spectrum inhibitors of influenza virus
Scientists have developed broad-spectrum inhibitors of the influenza virus using artificial peptide molecules...
Integrated drug discovery panel – your questions answered!
28 September 2017 | By Charles River
During this peer panel discussion, team members from Charles River discussed their views and strategies on Drug Discovery...
Novartis and UC Berkeley collaborate to tackle ‘undruggable’ disease targets
Collaboration aims to unlock difficult drug targets and accelerate the discovery of new medicines in areas such as infectious diseases and cancer...
Streamlined process opens drug development to a new class of steroids
Researchers have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries...
Potential therapeutic protein inhibitors for Chagas disease
Researchers have used a multi-modal integrated approach to develop potential new anti-Chagas therapies...
Webinar: Phenotypic assays for CNS disease drug discovery
21 September 2017 | By Charles River Laboratories
In this webinar, we highlight in vitro models and phenotypic assays to discover and validate novel targets and promising lead molecules...
Application note: Application of MultiCyt QBeads for high throughput cytokine profiling in human peripheral blood mononuclear cells
In this application note IntelliCyt Corporation report on the development and validation of their family of MultiCyt QBeads for the detection of cytokines in a high-throughput screening application on the iQue Screener...
Chemo-boosting drug discovered for leukaemia
Drugs developed to treat heart and blood vessel problems could be used to treat leukaemia...
Potential broad-spectrum antiviral discovery for herpes virus
Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...
MRC forges two new deals with industry to speed drug discovery
The Medical Research Council has formed partnerships with UCB and AstraZeneca, the deals will help speed translation of discovery research into potential therapies...
£8500 given to cancer research at the University of Warwick
Cancer research at the University of Warwick has received a boost thanks to the former Lord Mayor of Coventry Cllr Lindsley Harvard.
£2m grant for University collaboration antibiotic resistance study
Dr Reda Lebcir from the University of Hertfordshire is part of an international team of researchers awarded a £2m grant from the ESRC (Economic and Social research Council).