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Three-dimensional (3D) models are reshaping pre-clinical drug development by providing more accurate insights into drug safety and efficacy. Explore how these advanced in vitro systems help improve predictions and reduce the risk of failure in early-stage drug discovery.
In this first interview of a two-part series, Andreas Kolleger explores the convergence of knowledge graphs and large language models. As the head of GenAI innovation at Neo4j, Andreas brings a unique cross-industry perspective on how these technologies can enhance life sciences workflows.
GPCRs are crucial drug targets, but their complex structures present significant challenges in drug discovery. In this article, Domainex’s Philip Rawlins explores how fragment-based screening and innovative technologies like PoLiPa are helping to overcome these hurdles, with a focus on the Adenosine A2a receptor.
As cancer therapies evolve, a critical opportunity is emerging in the form of DNA Damage Response (DDR) research. With breakthroughs in genomics, drug delivery and AI, DDR pathways are set to overcome resistance and alter treatment strategies. Find out why now is the perfect moment to refocus on DDR, and…
Sartorius have published its second edition High-Throughput Screening (HTS) by Cytometry handbook.
Following high-throughput drug screening of the tumour organoids, an effective FDA-approved treatment was identified.
Tune in to this episode where we explore how innovative assays and human-relevant cell models are transforming toxicity screening in drug development.
Listen to this podcast where we explore the latest technological advancements in high throughput screening and more.
A 2D neuromuscular junction model enables high-throughput screening to discover new treatments for neuromuscular diseases.
Unleash the power of drug discovery with this FREE ebook supported by Sartorius! Explore the limitless potential of CRISPR applications and single cell sequencing for drug discovery. Access exclusive insights from industry leaders and stay ahead of the curve with the latest trends. Don't miss out on this opportunity to…
Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.
Matthew Lloyd from the University of Bath reveals the importance of the Z-factor and Z’-factor in high-throughput screening, and how they can be used to determine assay performance, perform quality control on the screen, and identify active compounds.
Transform your drug manufacturing process with the latest breakthroughs in technology. Effortlessly identify and differentiate degradation components of PS20 in protein-containing samples.
Tune into this podcast to hear experts discussing scaling up 3D organoids!
Tune into this podcast to hear experts discuss imaging and analysing data from organoids!
