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Nuclear PET imaging method developed for tumour detection
Researchers have developed a PET imaging method suitable for many forms of cancer, with high contrast and less inconvenience to patients...
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Expert view: New developments in real‑time live‑cell analysis
Live-cell analysis is now a well-established method that is part of the everyday cell biologist’s armoury for understanding cell biology. For over a decade, the functionality, throughput, and ease of use offered by real-time live-cell analysis has provided a platform for accurate and reproducible cell biology analysis in multiple biomedical…
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Scientists develop TSA-Seq technique for precise 3D mapping of human genome
Despite the human genome being first sequenced almost 20 years ago, researchers know comparatively little about how the genome is organised within cells. But a new TSA-Seq technique is changing that.
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Novel imaging biomarker to help predict coronary inflammation
Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality...
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Novel PET imaging could guide therapy for type 1 diabetes
Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...
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Exploring horizons in 3D microscopy: what the future holds
The microscope slide is flat (2D), but the world around us is not – despite the flat-earth theories. We need volume information about our samples, ideally with high resolution in all three dimensions as well as over time – the fourth dimension...
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Applications of molecular imaging in drug development
The world of healthcare is rapidly evolving. With an ageing population, comes a significant increase in cancers, metabolic diseases and neurodegenerative disorders. New drug candidates are required; however drug development remains a lengthy and expensive process, with the average timeline now over 10 years and costs continuing to rise...
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Improving the translation of disease biology though phenomics
How times change. Up to 15 years ago, you would be hard-pressed to find a drug discovery conference with a track dedicated to phenotypic approaches. The underpinning science was called high-content imaging or analysis, being mainly confined to academic drug discovery labs and a handful of pioneers in industry. but…
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New 3D ‘nanoscope’ facilitates improved brain imaging for Alzheimer’s research
Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.
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SPECT Imaging technique illuminates immune status of monkeys with HIV-like virus
Approach could improve understanding of immune system recovery in people treated for HIV infection...
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New software designed for rapid, automated identification of dendritic spines
Researchers release open source software, connecting and building the neuroscience coding community...
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Streamlining drug discovery assays for cancer and cardiovascular disease
For lead optimisation, target-based assays are still the most affordable means of rapidly performing fast iterations and remain core to screening. However, the desire for biological relevance is driving ongoing growth in cell-based assays.
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Expert view: Rising growth of the global high‑content screening software and services market
The global high-content screening (HCS) software and services market accounted for over $500 million in 2017 and is expected to reach approximately $1.4 billion by 2026, increasing at a compound annual growth rate of more than 11%, says Jeff McMillan, Senior Product Manager Imaging, Molecular Devices.
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ImmunoPET imaging noninvasively pinpoints colitis inflammation
A novel PET imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease...
