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Targeting immune cells may help treat atrial fibrillation
New MGH study finds that macrophages and macrophage-produced proteins contribute to heartbeat irregularities, thus targeting these cells can aid atrial fibrillation treatment.
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Immunology
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Double face of RNase as a treatment for systemic autoimmune diseases
Japanese research shows that treating systemic autoimmune diseases with RNases can be detrimental, depending on the composition of the immune complex.
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Specialised white blood cells could lead to more preventative treatments
Australian researchers analyse the way specialised white blood cells produce an immune response, which could lead to the development of preventative treatments for cancer and infectious diseases.
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Case study: Mitochondrial toxicity in drug discovery and development
The Agilent Seahorse XF assay platform has opened new avenues for examining mitochondrial health in a timely and effective manner.
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Pure capped mRNA vaccine encourages more effective vaccine development
Japanese researchers have designed a pure capped mRNA vaccine which has shown a better protein production in the immune system.
webinar
Innovations in organoid modelling for disease modelling and cell therapy
14 June 2023 | By Sartorius
Watch our virtual panel, where you'll uncover the game-changing advantages of organoids over traditional 2D cultures. Our experts will explore the immense potential of organoids in oncology and immuno-oncology research.
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Chemotherapy-free treatment for patients with blood cancer
Dr Andy Souers highlights the unwavering commitment to finding an enhanced therapeutic approach that eliminates the need for chemotherapy in blood cancer treatment. This transformative discovery represents a significant leap forward in the way we combat this complex disease, offering new hope to countless patients worldwide.
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Blocking a microRNA may prevent age-related conditions
Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
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T cells show immunity to a variety of bacteria
Australian scientists explored a group of bacterial pathogens that share a protein sequence which is recognised by human T cells.
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Inflammation ‘brake’ gene may impact kidney disease outcomes
Australian researchers uncover a gene that controls inflammation in kidney disease, which could pave the way for more precise disease diagnostics and personalised treatments.
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Resident T-cells key to salmonella immunity
According to US researchers, insights from mouse models of salmonella could lead to better vaccines and immunity.
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Accelerating the immune system could eliminate ageing cells
Boosting the body’s anti-viral immune response could restore tissue balance and eliminate ageing cells that contribute to age-related diseases.
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Artificial sweeteners weaken mice’s immune response to disease
New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.
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Analysis of 33 tumour types identifies new immunotherapy targets
The researchers identified 1,068 transposable element-derived transcripts with the potential to produce tumour antigens that could serve as targets for new immunotherapies.
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Webinar: The Role of Neuronal Metabolism in Early Drug Discovery
Learning about the mitochondrial role in a neurodegenerative disorder.
