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Nanomedicine

HIV cell being attacked by silver nanoparticles

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Combatting HIV using gene therapy

21 February 2024 | By Drug Target Review

Researchers have created a nanomedicine loaded with siRNAs, which demonstrated a 73 percent reduction in HIV replication.

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Revolutionary way to measure proteins aids precision medicine advancements

23 June 2023 | By Izzy Wood (Drug Target Review)

Using a nanofluidic aptamer nanoarray to measure biomolecules including proteins, Japanese researchers are attempting to bridge the gap for precision medicine

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Treating peanut allergies in mice with mRNA delivering nanoparticles

10 April 2023 | By Izzy Wood (Drug Target Review)

UCLA have developed technology using nanoparticles that deliver mRNA to liver cells, that could provide a platform to fight allergies.

Doctor or scientist shows a vial of genetic agent as a vaccine or therapy against Corona or Covid-19 as a symbolic image

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New study highlights lipid nanoparticles and mRNA could treat blindness

13 January 2023 | By Ria Kakkad (Drug Target Review)

The researchers developed nanoparticles able to penetrate the neural retina and deliver mRNA to the photoreceptor cells whose proper function makes vision possible.

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Nanotechnology: a new immuno-onocology weapon

8 December 2022 | By Izzy Wood (Drug Target Review)

This article outlines three innovative studies that use nanotechnology to deliver a new immunotherapy approach towards cancers.

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Nanotechnology platform sensitises cancer to immunotherapy

11 November 2022 | By Victoria Rees (Drug Target Review)

A new pre-clinical study has utilised nanoparticles to attach immune-activating molecules to cancer cells.

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AI helps produce nanozyme treatment to regenerate hair in mice

2 November 2022 | By Izzy Wood (Drug Target Review)

Researchers have used AI to design microneedle patches that restore hair in balding mice.

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Lipid nanoparticle delivery of mRNA could lead to new ‘universal’ COVID-19 treatment

19 October 2022 | By Victoria Rees (Drug Target Review)

A study has shown that mRNA delivered via lipid nanoparticles blocks multiple variants of SARS-CoV-2 from entering cells in mice.

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Drug Target Review’s highlights from ELRIG Drug Discovery 2022

6 October 2022 | By Ria Kakkad (Drug Target Review), Victoria Rees (Drug Target Review)

Victoria Rees and Ria Kakkad from Drug Target Review bring you the key takeaways from the ELRIG Drug Discovery 2022 event in London.

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Screening technique could accelerate and improve mRNA therapies

20 July 2022 | By Victoria Rees (Drug Target Review)

A new single-cell nanoparticle targeting-sequencing approach can measure the cellular uptake of lipid nanoparticles carrying mRNA therapies.

Image showing doctor examining newborn baby in incubator

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Nanotherapy could protect premature babies

31 March 2022 | By Ria Kakkad (Drug Target Review)

Pre-clinical research in newborn rats found that a nanotherapy could prevent chronic lung disease in premature babies.

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Novel nanotherapy offers hope for potential treatment of type 1 diabetes

18 January 2022 | By Nic Losardo (Drug Target Review)

Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.

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Nanoparticle delivery of CRISPR enables genome editing of vascular endothelium

6 January 2022 | By Victoria Rees (Drug Target Review)

According to researchers, a new method to deliver CRISPR-Cas9 to vascular endothelial cells could be used to treat many diseases, including COVID-19.

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Targeted nanomedicine reduces vascular lesions in mouse models

7 December 2021 | By Anna Begley (Drug Target Review)

The new nanoparticle uses a peptide to target the vascular cell adhesion molecule 1 and reduced the size of vascular lesions in a mouse study.

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Nanobubbles show promise for delivering anti-inflammation treatments

8 October 2021 | By Anna Begley (Drug Target Review)

Nanobubbles known as extracellular vesicles (EVs) were shown to deliver protein drugs in animal models with inflammatory diseases.

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Nanomedicine