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MicroRNA provides promise in search for simple, early test for Alzheimer’s
Researchers have found early evidence that tiny snippets of microRNA may help with early detection of conditions such as Alzheimer's disease...
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Neurosciences
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CRISPR-Gold used to reduce repetitive behaviours in FXS
Gold nanoparticles carried Cas9 enzyme into brain, editing receptor and lessening burying behaviour...
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Molecular alterations provide insight into Huntington’s disease
Scientists have applied their high-throughput, multi-pronged approach to Huntington's disease, and uncovered the functional significance of various molecular changes...
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Alpha-synuclein clumps promote Parkinson’s progression
Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...
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Link found between neurotransmitter imbalance and brain connectivity in those with autism
Researchers have identified a link between a neurotransmitter imbalance and brain connectivity between regions of the brain that play a role in social communication and language.
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Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.
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Expert view: Discovering neuronal cell types
Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.
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Tau mutations may increase cancer risk
Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...
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Three new genes linked to Alzheimer’s identified
An international research team has identified three new genes linked to the risk of Alzheimer’s disease...
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Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation
Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.
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SB216763 shows preclinical efficacy in Rett syndrome
Researchers describe how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome...
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Targeting cPLA2 may improve the treatment of epilepsy
New findings demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy...
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Cambinol halts spread of toxic protein associated with Alzheimer’s progression
Research could help lead to the design of drugs that slow neurodegeneration...
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Therapeutic RNA corrects splicing defect that causes familial dysautonomia
Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...
