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Protein

news

Cancer protein NEDD9 plays a critical role in PAH

14 June 2018 | By Dr Zara Kassam (Drug Target Review)

Study identifies cancer protein as a target for treating fibrosis of the lung arteries with direct implications for patients with pulmonary arterial hypertension...

news

Alpha-synuclein clumps promote Parkinson’s progression

14 June 2018 | By Dr Zara Kassam (Drug Target Review)

Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease...

news

Eosinophilic esophagitis may be due to missing SPINK7 protein

11 June 2018 | By Drug Target Review

NIH-funded study finds replacement therapy reversed effects in tissue experiments...

news

SMCHD1 protein found essential to X chromosome inactivation

8 June 2018 | By Dr Zara Kassam (Drug Target Review)

The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...

news

Scientists create ‘genetic atlas’ of proteins in human blood

7 June 2018 | By Drug Target Review

Researchers have created the first detailed genetic map of human proteins...

Eleen Shum, Manager, R&D Genomics Applications - BD

article

Expert view: Discovering neuronal cell types

4 June 2018 | By Eleen Shum (Manager - R&D Genomics Applications - BD)

Target the genes that matter for efficient sequencing and analysis with custom-targeted gene panels.

article

Supporting the progression of phenotypic hits with bioactivity profiling

4 June 2018 | By Drug Target Review

Bioactivity profiling has been traditionally used to assess the selectivity of new drug candidates in the context of target-based approaches, where pharmacological selectivity is a key requirement.

news

CRISPR approach could limit toxicity of CAR-T therapy in AML

4 June 2018 | By Dr Zara Kassam (Drug Target Review)

New study uses CRISPR/Cas9 to make CD33 CAR T cells cancer-specific...

news

Researchers use blood serum markers to develop lupus risk index

1 June 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed an index that identifies the risk for lupus based on the presence and amount of IgG and IgM antibodies and levels of C1q...

news

AIBP injection alleviates chemotherapy pain for months in mice

29 May 2018 | By Drug Target Review

Protein inhibits inflammatory response underlying chronic pain processing; may provide an alternative to opioids for severe, persistent pain...

news

Tau mutations may increase cancer risk

25 May 2018 | By Dr Zara Kassam (Drug Target Review)

Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...

news

Link between TB and Parkinson’s disease identified

23 May 2018 | By Dr Zara Kassam (Drug Target Review)

The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...

news

Blood test rapidly detects signs of pancreatic cancer

22 May 2018 | By Dr Zara Kassam (Drug Target Review)

A new diagnostic test developed by researchers at UC San Diego shows promise for detecting pancreatic cancer earlier...

news

CHRNA2 receptor proteins may help fat cells burn energy

22 May 2018 | By Drug Target Review

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells...

news

NMT molecule provides hope for common cold cure

21 May 2018 | By Drug Target Review

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells...

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Protein