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Stopping cancer cells in their tumour ‘highways’
Using controlled network microenvironments, tumour cells were prevented from travelling, which could prevent spread of the cancer throughout the body...
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Research & Development
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War On Cancer 2018: targeted therapies in oncology
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
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Muscular paralysis progression could be reduced using tamoxifen
Currently used for breast cancer, tamoxifen could be useful in preventing the progression of myotubular myopathy, a severe genetic disease...
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Preeclampsia symptoms alleviated by RNAi therapy
Animal models of preeclampsia have shown siRNAs can be used to reduce circulating sFLT1 in the blood, which could lead to treatments to prolong pregnancy...
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Inflammation inhibitor could be used to treat sepsis
An inhibitor that stops the action of OGG1 signals, could potentially be used as a treatment for life-threatening Acute Respiratory Distress Syndrome...
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PCSK9 inhibitors to treat high cholesterol
Low-density lipoprotein cholesterol could be treated by using synthetic DNA-encoded monoclonal antibodies to inhibit PCSK9...
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Inhibiting inflammation by blocking release of TNF alpha
Researchers at Karolinska Institutet collaborated with other researchers to develop a compound that prevents inflammation by blocking release of TNF alpha...
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Using anti-malaria drugs to slow tumour growth
Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...
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Spined soldier bug can be used to develop new classes of antibiotics
Researchers have identified the mechanism by which thanatin attacks the way the outer membrane of Gram-negative bacteria is built...
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Precision neuroengineering reproduces brain-like functions in vitro
Using precision engineering, researchers form Japan and Spain have collaborated to show brain-like functions in vitro to advance medical research...
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Immune cell enzyme protects against tuberculosis
Using lung tissue from humans and mouse models, researchers have found that HO-1 controls inflammation and protects against tuberculosis...
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Combination of imaging techniques views retina in unprecedented detail
Using two imaging techniques, adaptive optics and angiography, researchers have been able to view the retina in more detail than ever seen before...
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Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
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Defective damage repair to DNA results in chromosome chaos
German researchers have shown how defective damage repair to DNA results in chromothripsis - clustered chromosomal rearrangements...
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Vaccinia virus hijacks cellular movements to spread
To spread throughout the body, the vaccinia virus mimics the infected cells' own proteins enabling the cell to move around and spread...
