whitepaper
App Note: Faster and Easier Charge Heterogeneity Analysis with the iCE3
Three major usability improvements are now available for the iCE3 system...
List view / Grid view
Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
whitepaper
App Note: Total Protein Analysis the Simple Western Way
The Simple Western Immunoassay is the gel-free, blot-free and hands-free solution for those looking for a better way to get their Western blot data...
webinar
Phenotypic Screening in Drug Discovery
28 September 2015 | By Charles River
This webinar describes an approach to phenotypic discovery through bioprofiling in human primary cell-based assays across several disease areas (case study)...
article
Flow cytometry: Not just a box in the lab
Undoubtedly, you will have noticed the increase in the number of publications utilising flow cytometry, heard it mentioned more in meetings and probably even been targeted by several companies trying to sell you their latest cytometer. The rapidly advancing technology behind the cytometer and an increase in applications that use…
webinar
Immunology Screening on the iQue Screener
14 September 2015 | By IntelliCyt
Immunology Screening on the iQue Screener: Assays for Immune-Modulators and Immunotherapy...
news
New high-throughput screening method could speed drug discovery
19 August 2015 | By Victoria White
Scientists have developed a potentially better and more accurate high-throughput screening technique and have used it to identify 24 drug candidates...
video
The Science of Affimers
Find out about the science behind Affimers - including why Affimers are superior to antibodies and details about our custom Affimer process...
video
Affimers and Therapeutic Applications
Find out more about the applications of Affimers, including how Affimers can be used in the development of therapeutics...
article
Targeting cancer metabolism
Cancer cells are addicted to glucose and glutamine, which enables them to generate the energy and macromolecule synthesis intermediates to support their growth...
article
The importance of adequately triaging hits from HTS campaigns
High throughput screening (HTS) continues to be employed in drug discovery as the primary source of identifying chemical starting points for drug discovery and tool compounds for chemical biology, respectively. Although small molecule drug discovery efforts have focused largely upon enzyme, receptor and ion-channel targets, there has been an increase…
video
An Introduction to Avacta Life Sciences
This video introduces Avacta Life Sciences, part of Avacta Group plc and its flagship product, Affimers - a revolutionary new, engineered alternative to antibodies...
article
Human pluripotent stem cell-derived cardiomyocytes in drug discovery and development
Procedures for cardiac differentiation of human pluripotent stem cells (hPSCs) have greatly improved over the past few years. The facilitated derivation of hPSC-cardiomyocytes has enabled the thorough assessment of their physiology and manipulation of their properties. Moreover, patient-specific hPSCs generated through cellular reprogramming allow for cardiac disease modelling, discovery of…
article
Screening In-Depth Focus 2015
10 June 2015 | By Kenji Schorpp, Kamyar Hadian, Sheraz Gul, Horst Flotow
In this Screening In-Depth Focus, high throughput screening is the topic focused on by Kenji Schorpp and Kamyar Hadian, Institute of Molecular Toxicology and Pharmacology, and Sheraz Gul, Fraunhofer Institute for Molecular Biology and Applied Ecology. They discuss the importance of the technique in drug discovery today as well as…
article
True screening for immunology: transforming science with a practical tool for large-scale discovery
10 June 2015 | By IntelliCyt Corporation
The immune system plays a vital role in keeping us alive but also participates in many diseases adversely affecting quality of life across the globe. It can be over activated, leading to a variety of inflammation and autoimmune diseases, or suppressed, leading to a vast array of diseases from AIDS…
article
From hype to hope: challenging the norm in lead discovery
From the beginning of time in the drug discovery world, the integration of disciplines has driven the identification of new lead molecules. Chemists, pharmacologists and biologists work together to understand a disease state and how to perturb that state back towards a normal healthy condition. However, in the early days…
