Proteogenomics research – on the frontier of precision medicine
Posted: 14 December 2017 | Alicia Landeira, Javier Carabias, Jonatan García, Manuel Fuentes (Cancer Research Centre), Maria Gonzalez-Gonzalez, Paula Díez (Cancer Research Centre), Rafael Góngora, Rodrigo Garcia-Valiente | No comments yet
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
The principle of ‘omics’ approaches is the analysis in high-throughput format of genes/mRNA/proteins/metabolites presented in a biological sample and are called genomics, transcriptomics, proteomics and metabolomics, respectively. Nowadays, these omics approaches are becoming more relevant due to their application in biomedicine (such as novel drugs, novel biomarkers, earlier diagnosis, novel therapeutic targets, etc).1,2,3,4,5
University of Salamanca