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Expert view: Following mitchondrial substrate oxidation pathways to expose novel drug targets

Posted: 12 December 2019 | | No comments yet

Energy metabolism drives everything we do, so it is no surprise that the more we discover about these metabolic processes, the more we observe seamless integration with all core cellular functions.

Metabolism now sits at the heart of incredibly exciting discoveries across diverse research areas, exemplified by evidence that the metabolic phenotype and/or tumour microenvironment impacts cancer progression and therapeutic efficacy and that metabolic poise is a key driver of immune cell fate and function.

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