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ALS

Blood-brain barrier (BBB) in the human brain - closeup view 3d illustration

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Blood-brain barrier breakthrough for ALS and Alzheimer’s disease

27 November 2024 | By Drug Target Review

A new blood-brain barrier-crossing platform enables the delivery of therapeutic molecules to the brain, offering potential treatments for ALS and Alzheimer’s disease.

news

Stealth BioTherapeutics reports positive pre-clinical data for ALS candidate

11 October 2021 | By Anna Begley (Drug Target Review)

Stealth BioTherapeutic's SBT-272 improved mitochondrial motility in a murine model of amyotrophic lateral sclerosis.

news

Self-cannibalising mitochondria discovery may lead to ALS treatment target

19 November 2019 | By Rachael Harper (Drug Target Review)

A new phenomenon in the brain that could explain the development of early stages of neurodegeneration has been discovered which could lead to a future target for drug therapies for ALS.

news

New tools accurately illuminates intracellular phase separation

30 November 2018 | By Drug Target Review

Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...

news

Sensory neurons can be used to discover therapies for ALS

9 November 2018 | By Drug Target Review

New approach for testing for ALS may be useful to reverse debilitating disease...

news

Better drug delivery through the blood-brain barrier

19 October 2018 | By Iqra Farooq (Drug Target Review)

Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue...

news

Class of neurological disorders share 3D genome folding pattern

19 September 2018 | By Drug Target Review

Researchers have found another common thread linking nearly all of the TNR expansion diseases...

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Recommended

ALS

Blood-brain barrier breakthrough for ALS and Alzheimer’s disease

Stealth BioTherapeutics reports positive pre-clinical data for ALS candidate

Self-cannibalising mitochondria discovery may lead to ALS treatment target

New tools accurately illuminates intracellular phase separation

Sensory neurons can be used to discover therapies for ALS

Better drug delivery through the blood-brain barrier

Class of neurological disorders share 3D genome folding pattern