Imaging

IDEA Bio-Medical Ltd.

Drug Target Review – Issue #1 2017

9 March 2017 | By Drug Target Review

Included in this issue: Importance of building patient trust; Vaccines & Immunology; Oncology; Assays; Biomarkers; and Antibodies...

How imaging biomarkers are transforming drug development

15 January 2017 | By Caleb Roberts, John Waterton, Juliana Maynard, Paul Hockings

Drug developers sometimes think of imaging as an emerging discipline, full of esoteric technologies of marginal relevance to real-world clinical drug development. In fact, the opposite is true: imaging measurements (imaging biomarkers) are used daily in drug development and in personalised medicine. They assess target engagement and receptor occupancy in…

High-throughput screening platforms incorporating physiologically relevant 3-D models

8 January 2017 | By Anton Simeonov, Madhu Lal-Nag

Two-dimensional monolayer cell proliferation assays for cancer drug discovery have enabled large-scale screens. But they represent a simplified view of oncogenes or tumour suppressor genes as the genetic drivers of cancer cell proliferation.

Researchers develop new retinal imaging technique

3 January 2017 | By Niamh Marriott (Drug Target Review)

Researchers at the University of Rochester Medical Centre have developed a new imaging technique to better assess eye health and potential disease.

PathHunter® Protein Translocation Assays

21 December 2016 | By DiscoverX Corporation

The movement of proteins between cellular compartments is essential for their specific biological role and the function of the cell...

Diabetic research suggests purslane herb extract mimics insulin

20 December 2016 | By Niamh Marriott (Drug Target Review)

A new study has confirmed the anti-diabetic properties of the purslane herb extract Portulaca oleracea L.

Molecular Devices

€3.3 million to improve medical imaging detail tenfold

3 November 2016 | By Niamh Louise Marriott, Digital Content Producer

A recent investment of €3.3 million will allow researchers to improve the detail of medical imaging ten times over, which will allow for tumour scanning...

Charles River Laboratories acquires Agilux Laboratories, Inc.

13 October 2016 | By Charles River Laboratories

Enhances Charles River’s early-stage capabilities in bioanalytical services...

Whitepaper: Uncover specific correlations in heterogeneous cell populations during drug development

3 October 2016 | By Bio-Rad Laboratories

Integrating the S3e™ Cell Sorter into sample preparation upstream of the QX200™ Droplet Digital System provided details about cell subpopulations that would have been undetectable in heterogeneous populations...

How the anthrax toxin forms a deadly “conveyer belt”

28 September 2016 | By Niamh Louise Marriott, Digital Content Producer

During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...

Charles River Laboratories and The Tri-Insitutional Therapeutics Discovery Institute announce strategic partnership

26 September 2016 | By Charles River Laboratories

Partnership intends to accelerate translation of discoveries into novel therapies for patients...

Imaging In-Depth Focus 2016

20 September 2016 | By Debra Taylor, Emilie Bureau, Janet Brownlees, Jenny Cook, Norman Peterson

In this Imaging In-Depth Focus: Norman Peterson, from MedImmune/AstraZeneca, looks at the practical application of in vivo optical imaging in biotherapeutic biodistribution analyses. Plus, experts from MRC Technology discuss high-content imaging in drug discovery, and Molecular Devices feature in our Q&A...

Intercontinental consortium granted €5.1 million to develop breast cancer imaging devices

15 September 2016 | By Niamh Louise Marriott, Digital Content Producer

Grants of more than €5 million, predominantly from the EU, will be used to develop a new imaging device for the diagnosis of breast cancer...