news
Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...
List view / Grid view
Omics
news
Detecting epigenetic signature may help people stay ahead of IBD
Researchers have reported finding on an epigenetic signature in patient cells that appears to predict inflammation risk in Crohn's disease...
news
New understanding of T-cell receptor behaviour presents challenge for immunotherapies
Researchers in the U.S. have made a surprising discovery about the binding behaviour of a particular T-cell receptor, with complicated ramifications for immunotherapy developers.
news
Scientists develop means to manipulate nuclear pore numbers
Researchers in California have developed a method to facilitate control of nuclear pore numbers in cells. The capability is expected to glean valuable information to aid cancer treatment.
news
Class of neurological disorders share 3D genome folding pattern
Researchers have found another common thread linking nearly all of the TNR expansion diseases...
news
Small molecule factors found to influence age-related bone deterioration
Scientists in the U.S. have reported findings about the mechanisms that contribute to the experience of weaker bones with age.
news
CRISPR used to deliver BChE into cells to protect from lethal cocaine doses
Researchers have described a novel approach that was able to stifle the desire for cocaine and to protect against an overdose...
news
Method developed to facilitate effective protein drugs with fewer side effects
Researchers in Denmark have developed a method that enables better tailored pharmaceuticals with fewer side effects.
news
Disrupting genetic processes reverses ageing in human cells
Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age...
article
Synthetic biology in drug discovery
Synthetic biology is broadly defined as the design and construction of novel artificial biological pathways, organisms or devices; or the redesign of existing natural biological systems.1 It brings together a range of disciplines and skills, from biology and chemistry to computing, bioinformatics and engineering.
news
Unique method to find cancer mutations offers chance of improved treatment
Researchers have condensed methods for identifying cancer gene mutations in cells into a single process, to aid understanding of tumours and improve treatment outcomes.
article
Expert view: The development of single‑cell genomics with Smart‑seq
Takara Bio has played a major role in the development of single-cell genomics with the launch of kits such as the automation-ready Smart-seq HT, with a simplified 4-steps protocol. In addition, to meetthe demand for using RNA-seq for degraded clinical samples, we have expanded our offering with a complete sequencing…
news
Blocking RNA-silencing protein Ago2 shows promise for obesity prevention
Researchers are hopeful of finding a means to inhibit obesity and its associated health problems after a study in which they blocked an RNA-silencing protein in the livers of mice, preventing obesity and diabetic conditions.
news
Carving a pathway toward personalised cancer therapy
Individualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, treatment and care. However, several challenges remain before these approaches can be widely used in the clinic.
article
Expert view: Unravelling the complexities of GABAA subunit selectivity in drug discovery
GABAA receptors represent a large and complicated family of ion channels that consist of at least 16 subunits (α1-6, β1-3, γ1-3, δ, ε, π, θ) that have been shown to be vital for the normal functioning of the brain. These inhibitory ligand-gated channels have been shown to beimportant in sedation,…
