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Whitepaper: Neurodegeneration therapeutics discovery
Advance your neurodegeneration research with our broad antibody portfolio, ready-to-use ELISA, and cellular kits to develop new efficacious therapies.
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SARS-CoV-2 antibodies can bind to two viral targets at once
US researchers find that SARS-CoV-2 bivalent antibodies can continue to neutralise Omicron and Omicron lineages.
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The advantages of gamma-delta T-cell therapy
Here, Dr Michael Leek describes the benefits of gamma-delta T cells for cancer therapy, exploring why they present a potential alternative to other immuno-oncology platforms.
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Novel therapeutic approach aims to prevent ARDS
UCLA researchers have found peptide blocks that cause the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.
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Major lung cancer mechanism can be used to evade immune attack
US researchers found high levels of XBP1s in lung cancer cells, which plays a key part in regulating the local immune environment in lung tumours, and can be disabled to increase anti-cancer immunity
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Application note: Real-time kinetic analysis of Akt activity
Cell signalling through the Akt pathway controls numerous key cellular functions including proliferation, survival, and migration.
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New study highlights lipid nanoparticles and mRNA could treat blindness
The researchers developed nanoparticles able to penetrate the neural retina and deliver mRNA to the photoreceptor cells whose proper function makes vision possible.
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A change in genetic code causes lung cancer to develop
Using lung basal cell organoids, researchers identify a gene that directs the development of lung cancer and offers a better understanding of its disease treatment.
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Mathematical model predicts long-term effectiveness of COVID-19 vaccine
US scientists have designed a mathematical model that can predict COVID-19 vaccines’ effectiveness over the long term in healthy individuals and those who have cancer or suppressed immune responses.
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Study identifies gene and proteins that could treat dry eye disease
Researchers found that proteins made by stem cells that regenerate the cornea could be new targets for treating dry eye disease.
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New insights on the structural biology of medical cannabis
French researchers underwent a structural study showing that THC cannabinoids inhibit a human enzyme called autotaxin.
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Could drinking green tea, red wine and beer prevent Alzheimer’s?
In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.
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Humanised mouse model identifies the best match for organ donor
US researchers have developed a mouse model that holds promise in identifying the best organ donor and showing early signs of transplant rejection.
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Memory loss could be solved using an asthma drug
Dutch researchers, using optogenetic approaches and an asthma drug, discovered that memory loss from sleep deprivation can be retrieved.
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Novel protein coordinates melanin production
Japanese researchers reported that a key transcription factor “Nrf3” regulates the process of melanin production in mouse and human cells.
