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Issue #1 2015



Drug Target Review – Issue #1 2015

9 April 2015 | By J.R. Costa, J. Heintze, R. Ketteler, K. Papenfuss, C. Richards, S. Nahnsen, N. Graffman, P. Matz, W.Wruck, J. Adjaye, C. Williams, W. Fecke.

In this issue: Next-Generation Sequencing, Drug Targets, High Throughput Screening, Phenotypic Screening, Stem cells, Label-Free technologies and Assays...


NGS In-Depth Focus 2015

9 April 2015 | By Caroline Richards, Editor, Drug Target Review

In this NGS In-Depth Focus; How next-generation sequencing came to be, plus a brief history & Data management for large-scale NGS-based research projects...


Drug Targets In-Depth Focus 2015

9 April 2015 | By J.R.Costa, J.Heintze, R.Ketteler, S. Gul, Dr. T.Duensing, K.Papenfuss.

In this Drug Targets In-Depth Focus, we delve into the role of a key complex required for autophagosome maturation, the ATG4-ATG8 conjugation system, and we provide insight on some up-and-coming immune checkpoint inhibitors that are currently in clinical and preclinical development...


Label-free technologies for monitoring drug interactions

9 April 2015 | By ,

In his fascinating overview of label-free analysis, Dr. Masson introduces the four main label-free methods: physical, electrochemical, mass-based and optical techniques, before providing the reader with in-depth insight into the most common label-free technique within the pharmaceutical industry: surface plasmon resonance (SPR)...