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13 January 2016 | By Victoria White
Boehringer Ingelheim and Arena Pharmaceuticals have signed an exclusive agreement to conduct joint research to identify drug candidates for psychiatric diseases...
12 January 2016 | By Victoria White
The first four investments of the newly focused initiative include $46 million in financing to companies at early stages of the discovery process that are actively exploring Conditionally Active Biologics (CABs), immuno-oncology, neurodegenerative technologies and gene therapy...
12 January 2016 | By Victoria White
A new study describes the design of a CAR architecture with an integrated switch-on system that permits control over CAR T-cell functions...
12 January 2016 | By Victoria White
The acquisition includes IOmet's comprehensive preclinical pipeline of IDO (indoleamine-2,3-dioxygenase 1), TDO (tryptophan-2,3-dioxygenase), and dual-acting IDO/TDO inhibitors...
12 January 2016 | By Victoria White
Cortical spreading depressions (CSDs) are believed to be responsible for the aura, or visual disturbance, that frequently precedes some migraines, and have been a significant target for pharmaceutical development...
12 January 2016 | By Victoria White
ReNeuron is researching the therapeutic potential of exosomes derived from its proprietary stem cell lines. The Company is also exploring the potential of its exosomes as a delivery system for gene therapy treatments...
11 January 2016 | By Victoria White
The collaboration will focus on the development of drugs targeting important human oncogenes, including RAS, and new antibiotics targeting Gram-negative bacteria...
11 January 2016 | By Victoria White
mRNA-based therapies are an innovative treatment approach that enables the body to produce therapeutic protein in vivo, opening up new treatment options for a wide range of diseases...
11 January 2016 | By Victoria White
The proceeds will support the development of Aelix’s lead candidate HTI immunogen as a therapeutic vaccine against HIV infection up to the completion of a Phase 2 proof-of-concept efficacy trial in HIV-infected individuals...
11 January 2016 | By Victoria White
The agreement gives Novartis access to four preclinical programmes that target regulatory T-cell populations, inhibitory cytokines, and immunosuppressive metabolites in the tumour microenvironment...
11 January 2016 | By Victoria White
The companies will work together on the generation and evaluation of up to two bispecific NK cell engagers, using technology from Innate and Sanofi's proprietary bispecific antibody format as well as tumour targets...
8 January 2016 | By Victoria White
The partnership will focus on the delivery of recombinant Glial Cell Line-Derived Neurotrophic Factor to affected brain regions by way of implanted, encapsulated cell therapy devices...
8 January 2016 | By Victoria White
The virtual laboratory will establish the environmental impact of drugs earlier in discovery and development while dramatically reducing both the cost of environmental assessments and the need for animal testing...
8 January 2016 | By Victoria White
The first-in-class candidate, CB1, has shown potent anti-metastatic activity, and with an impressive in vivo efficacy and safety profile...
8 January 2016 | By Victoria White
Researchers have shown that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells...
