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MabVax files IND with the FDA for HuMab 5B1

2 December 2015 | By Victoria White

In preclinical research, the 5B1 antibody has demonstrated high specificity and affinity, and has shown potent cancer cell killing capacity and efficacy in animal models of pancreatic, colon and small cell lung cancers...

CFTR interacts with the wrong partners in cystic fibrosis

30 November 2015 | By Victoria White

By removing these interactions, the researchers partially restored the protein’s normal function. The findings suggest that therapies could one day treat the root cause of cystic fibrosis, not just the symptoms...

Heptares and Pfizer to focus on GPCR targets

30 November 2015 | By Victoria White

Heptares and Pfizer have announced they are to research and develop potential new medicines directed at up to 10 G protein-coupled receptor (GPCR) targets across multiple therapeutic areas...

Sleeping sickness project passes 20-month milestone

30 November 2015 | By Victoria White

The aim of the project is to design a drug to inhibit a key parasite enzyme involved in the conversion of blood sugars to energy, to be effective in small doses, even on advanced infections, and kill the parasite...

Scientists create therapeutic venom database

26 November 2015 | By Victoria White

Venom Knowledge Base summarises the results of 5,117 studies in the medical literature describing the use of venom toxins as painkillers and as treatments for diseases...

Gene map identifies genes unique to different cancers

26 November 2015 | By Victoria White

Scientists from the University of Toronto have switched off, one by one, almost 18,000 genes - 90% of the entire human genome - to find the genes that are essential for cell survival...