Japanese researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects.
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University of Tokyo
New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.
A team has developed a lotus-root-shaped construct to deliver iPSC-derived pancreatic beta-cells to patients with type I diabetes mellitus.
A team has developed enterocyte-like cells from hiPSCs, which can be used to study the absorption of novel oral drugs.
A team has developed 10 new versions of the antibiotic gramicidin A, which they say should be safe for use in pills or injections.
Enhancing neuromuscular junction (NMJ) formation using DOK7 gene therapy improved muscle strength and motor function in aging mice.
Researchers have demonstrated that Nafamostat mesylate (Fusan) can inhibit SARS-CoV-2 Spike protein-initiated membrane fusion at concentrations likely achievable and safe in patients.
In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.
Researchers collaborated to identify the clearest image of the Ebola virus protein ever obtained using a cryo-electron microscope...