US researchers found high levels of XBP1s in lung cancer cells, which plays a key part in regulating the local immune environment in lung tumours, and can be disabled to increase anti-cancer immunity
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Weill Cornell Medicine
The scientists argue the technique enables the creation of complex, data-rich “maps” of organs, including diseased organs and tumours, which could be widely useful in pre-clinical research.
The research has shown in high-resolution detail how certain lipids interact with pacemaker ion channels to enhance their activity.
Scientists have found antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from cytomegalovirus.
New research has uncovered a hitherto unknown mechanism whereby chemokines form DNA-bound nanoparticles that play a key role in autoimmune disorders.
Researchers have developed a two-step approach using whole exome sequencing to focus on genes and pathways that predict whether cancer patients will respond to immunotherapy.
A new study in mice has highlighted that gut beneficial bacteria can be transferred from mothers to infants through breast milk and help infants defend against infection-induced diarrheal illness.
Researchers have identified a previously unrecognised form of hormone therapy-resistant prostate cancer.
A new study has highlighted an enzyme called ART1 as a promising target for immunity-boosting cancer treatments.
Researchers have found a small subset of antibodies that target a site at the base of the influenza virus hemagglutinin protein.
Two groups of infant rhesus macaques received one of two potential COVID-19 vaccines, which were shown to elicit high levels of neutralising antibodies.
A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.
Researchers have used imaging mass cytometry to analyse the cellular landscape of diseased lung tissue in severe COVID-19, revealing insights into the disease.
A version of the FOXO3 gene can protect brain stem cells from stress during ageing, according to a new study.