Potential for personalised, molecularly guided UTUC treatments
The findings from DNA and RNA sequencing in primary and metastatic UTUC tumours could lead to strategies to improve patient outcomes.
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The findings from DNA and RNA sequencing in primary and metastatic UTUC tumours could lead to strategies to improve patient outcomes.
Using tumour organoids, researchers have found a starting point for the development of a more refined PDAC drug.
US researchers found high levels of XBP1s in lung cancer cells, which plays a key part in regulating the local immune environment in lung tumours, and can be disabled to increase anti-cancer immunity
The scientists argue the technique enables the creation of complex, data-rich “maps” of organs, including diseased organs and tumours, which could be widely useful in pre-clinical research.
A US study used an AI algorithm to determine chromosomal numbers in IVF embryos.
The research has shown in high-resolution detail how certain lipids interact with pacemaker ion channels to enhance their activity.
Scientists have found antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from cytomegalovirus.
New research has uncovered a hitherto unknown mechanism whereby chemokines form DNA-bound nanoparticles that play a key role in autoimmune disorders.
Researchers have developed a two-step approach using whole exome sequencing to focus on genes and pathways that predict whether cancer patients will respond to immunotherapy.
A new study in mice has highlighted that gut beneficial bacteria can be transferred from mothers to infants through breast milk and help infants defend against infection-induced diarrheal illness.
Researchers have identified a previously unrecognised form of hormone therapy-resistant prostate cancer.
A new study has highlighted an enzyme called ART1 as a promising target for immunity-boosting cancer treatments.
Researchers have found a small subset of antibodies that target a site at the base of the influenza virus hemagglutinin protein.
Two groups of infant rhesus macaques received one of two potential COVID-19 vaccines, which were shown to elicit high levels of neutralising antibodies.
A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.