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Sheraz Gul

 

Lab Automation In-Depth Focus 2018

In this issue: how lab automation has accelerated pharmaceutical research…

16 March 2018 | By

In this issue: how lab automation has accelerated pharmaceutical research by simplifying operations, reducing manual tasks and increasing the efficiency, quality and reproducibility of results.

Identification of hits and leads for human African trypanosomiasis

Neglected tropical diseases (NTD) affect more than one billion people…

13 December 2017 | By , ,

Neglected tropical diseases (NTD) affect more than one billion people and new targets and drugs are needed to tackle these infections. The multi-disciplinary NMTrypI consortium has identified a number of different compound classes which could be effective against these diseases. This article reviews some of these compounds...

Informatics In-Depth Focus 2017

In this In-Depth Focus we look at using bioinformatics sequence…

8 December 2017 | By

In this In-Depth Focus we look at using bioinformatics sequence similarities to optimise repurposing activities; informatics infrastructure in neglected disease research, and machine learning for accelerating drug discovery.

Hit To Lead In-Depth Focus 2017

In this In-Depth Focus we look at a pragmatic approach…

6 December 2017 | By

In this In-Depth Focus we look at a pragmatic approach to hit validation following biochemical high-throughput screening as well as identification of hits and leads for human African trypanosomiasis.

Structure based drug discovery facilitated by crystallography

Drugs exert therapeutically meaningful effects if they bind with appropriate…

15 September 2017 | By ,

Drugs exert therapeutically meaningful effects if they bind with appropriate selectively and potency to their respective targets. Although many of the assay techniques employed in early-stage drug discovery provide evidence that a drug is acting upon the target under investigation, this is often indirect and the site of action and…

Assays In-Depth Focus 2017

This in-depth focus looks at improving assay techniques to produce…

8 September 2017 | By

This in-depth focus looks at improving assay techniques to produce more detailed results using crystallography. It also covers some aspects of high-content screening assay development that are critical to successful implementation...

Drug Target Review – Issue #3 2017

Included in this issue: The importance of industry partnerships; Calcilytics…

6 September 2017 | By

Included in this issue: The importance of industry partnerships; Calcilytics as potential novel therapeutic treatments to halt Alzheimer's disease; Accelerating neuroscience research with flow cytometry...

Screening In-Depth Focus 2017

Included in this Screening In-Depth Focus: Phenotypic and target-based screening;…

5 June 2017 | By

Included in this Screening In-Depth Focus: Phenotypic and target-based screening; Killing cancer cells using clinical drug resistance; Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool...

Under the microscope with Labcyte

Dr Sheraz Gul, Head of Assay Development and Screening at…

15 March 2017 | By

Dr Sheraz Gul, Head of Assay Development and Screening at the Fraunhofer Institute for Molecular Biology and Applied Ecology, answers questions on assay procedures...

Stem Cells In-Depth Focus 2016

Featured in this Stem Cells In-depth Focus: Translating stem cell…

16 June 2016 | By , , , ,

Featured in this Stem Cells In-depth Focus: Translating stem cell biology into drug discovery; Mechanism-informed phenotypic screening – the missing link for cancer drug discovery; Analysis of human stem cell interactions at the single-cell resolution...

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