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Identification of hits and leads for human African trypanosomiasis

Neglected tropical diseases (NTD) affect more than one billion people and new targets and drugs are needed to tackle these infections. The multi-disciplinary NMTrypI consortium has identified a number of different compound classes which could be effective against these diseases. This article reviews some of these compounds…

Identification of hits and leads for human African trypanosomiasis

According to the World Health Organization, neglected tropical diseases (NTD) are a diverse group of communicable diseases that are prevalent in many tropical and sub-tropical regions and affect more than one billion people. These regions are associated with poverty and lack of suitable sanitation, and their populations are in close contact with infectious vectors. The situation is further confounded by the lack of new drugs being developed to treat these diseases.

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