Analysis

New drug target for glioblastoma identified by study

21 August 2019 | By Rachael Harper (Drug Target Review)

A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.

Tosoh Bioscience

New study reveals causes of stem cell transplant rejection

20 August 2019 | By Rachael Harper (Drug Target Review)

A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.

Optofluidic chip platform developed for single molecule analysis

19 August 2019 | By Rachael Harper (Drug Target Review)

A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.

Genes responsible for gender differences in tumours identified

19 August 2019 | By Rachael Harper (Drug Target Review)

A new study has identified possible regulators that determine differences in cancer tumours between genders.

Genes linked to Alzheimer’s risk have been identified

15 August 2019 | By Nic Losardo (Drug Target Review)

Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.

Blood-brain barrier role in Alzheimer’s patients revealed by tissue model

13 August 2019 | By Rachael Harper (Drug Target Review)

A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.

Therapeutic target for Kennedy’s disease and prostate cancer proposed

9 August 2019 | By Rachael Harper (Drug Target Review)

A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.

Potential treatment target identified for Crohn’s disease

9 August 2019 | By Rachael Harper (Drug Target Review)

Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.

New drug could be used for targeted cancer therapies

7 August 2019 | By Rachael Harper (Drug Target Review)

A new drug called IP1867B, which could be used for future treatments of brain tumours, is being examined.

New model predicts cognitive decline two years ahead

6 August 2019 | By Rachael Harper (Drug Target Review)

Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.

Experimental treatment slows prion disease

5 August 2019 | By Rachael Harper (Drug Target Review)

A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice

OX40-expressing follicular helper T cells can control rheumatoid arthritis

1 August 2019 | By Rachael Harper (Drug Target Review)

New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.

Study of TP53 mutations shows insight into the gene’s function

31 July 2019 | By Drug Target Review

New study sheds light on how the TP53 gene becomes mutated and how those mutations can help predict clinical outlooks for cancer.

Measuring the affinity of challenging protein targets

31 July 2019 | By Fluidic Analytics

Join us as we discuss the latest data from the literature and application studies where diffusional sizing (MDS) is used to assess a variety of protein interactions – even of difficult targets.