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14 January 2019 | By Iqra Farooq (Drug Target Review)
A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.
9 January 2019 | By Drug Target Review
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
7 January 2019 | By Drug Target Review
Satellite imaging could revolutionise imaging in laboratories, and may impact the current use of imaging in medicinal research...
2 January 2019 | By Iqra Farooq (Drug Target Review)
Streptomyces bacteria has been used to identify compounds that could lead to the production of drugs to treat various conditions...
11 December 2018 | By SB Drug Discovery
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
10 December 2018 | By Iqra Farooq (Drug Target Review)
Liquid-phase electron microscopy could overcome limitations identified through traditional protein imaging techniques and through cro-electron microscopy...
10 December 2018 | By Anowarul Amin
In the wake of the human genome project, molecular biology and genetic technologies are tremendously integrating into biomedical research. Currently, PCR, qPCR, and sequencing are key tools in the clinical laboratory for the detection and characterisation of microorganisms and genetic disorders.
High-throughput screening (HTS) technologies have enabled the routine testing of millions of compounds towards the identification of novel ‘hit’ molecules for therapeutic targets. Oftentimes in this drug discovery process, however, compounds that show promising activity in primary screens show no activity during subsequent hit qualification or progression efforts.
3 December 2018 | By Drug Target Review
A lower quantity of contrast protein, in comparison to current methods, has obtained clear, high-resolution images from magnetic resonance imaging...