Analytical Techniques

Droplet Digital PCR detects and quantifies cancer mutation

31 October 2018 | By Drug Target Review

Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...

MRI tool to cure digestive disorders

26 October 2018 | By Drug Target Review

Purdue researchers have paved the way for more precise treatment for disorders in the gastrointestinal tract such as gastroparesis...

3D image of insulin and its receptor revealed

25 October 2018 | By Iqra Farooq (Drug Target Review)

After combining over 700,000 2D images, researchers have finally been able to build a 3D image of how insulin binds to its receptor...

Single molecule fluorosequencing to transform biological research

22 October 2018 | By Iqra Farooq (Drug Target Review)

Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...

Critical cancer immunity genes identified using genetic barcoding

22 October 2018 | By Iqra Farooq (Drug Target Review)

Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...

Clearest image of Ebola virus protein gained by researchers

18 October 2018 | By Drug Target Review

Researchers collaborated to identify the clearest image of the Ebola virus protein ever obtained using a cryo-electron microscope...

RNA molecule nc886 could unlock innate immunity

15 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified that the RNA molecule nc886 begins a series of events that leads to the destruction of viruses...

Elrig 2018: Drug discovery using small and large molecules

9 October 2018 | By Iqra Farooq (Drug Target Review)

The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...

NIH to build cell atlas of the human body

28 September 2018 | By Iqra Farooq (Drug Target Review)

The NIH's Common Fund programme looks towards building a cell map of all individual cells in the human body to aid the detection of disease...

Agilent Technologies

Mass spectrometry and drug development – how the two come together

22 September 2018 | By Manfred Raida (National University of Singapore)

Since the development of the so-called soft ionisation techniques: electrospray ionisation and matrix-assisted laser desorption and ionisation in the 1980s and early 1990s and the development of high-resolution mass spectrometers, mass spectrometry (MS) has come to the fore in studying complex biological systems...

Np63a should be targeted in squamous cell carcinomas

19 September 2018 | By Iqra Farooq (Drug Target Review)

A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...

Six compounds identified from 70,000 to help eradicate malaria

18 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...

Enhanced 3D neuron imaging could diagnose brain disease

13 September 2018 | By Drug Target Review

Researchers have combined an open source software programme and commercially available hardware to image neuron activity at high resolution...

Transparent high-resolution EEG array allows brain imaging

7 September 2018 | By Drug Target Review

Researchers have developed a see-through, dual-layered, mesh EEG device which is capable of measuring the electrical activity of individual neurons...