PAINS management: an open source model to eliminate nuisance compounds
Posted: 4 December 2018 | Stephen J. Capuzzi and David C. Morris (Eshelman School of Pharmacy - University of North Carolina Chapel Hill) | No comments yet
High-throughput screening (HTS) technologies have enabled the routine testing of millions of compounds towards the identification of novel ‘hit’ molecules for therapeutic targets. Oftentimes in this drug discovery process, however, compounds that show promising activity in primary screens show no activity during subsequent hit qualification or progression efforts.
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Related topics
Analysis, Analytical techniques, Drug Discovery, Hit-to-Lead, Research & Development, Screening, Therapeutics
Related organisations
North Carolina University
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