article

Drug Target Review – Issue 4 2018

Posted: 26 November 2018 | | No comments yet

In this issue: Omics-informed drug target discovery in combating emerging infectious diseases, measuring intracellular ATP levels to access compound-mediated cellular toxicity, and turning organoids into physiologically relevant high-content assays for drug discovery.

Drug Target Review issue 4 2018

In this issue:

  • UNDER THE MICROSCOPE: Under the microscope: CROs and microplate reader requirements
    BMG Labtech
  • APPLICATION NOTE: Automated cell transfection and reporter gene assays
    Beckman Coulter 
  • IN-DEPTH FOCUS: Screening
  • ORGANOIDS: Beyond ‘simple’ biology – turning organoids, spheroids, and 3D tissue models into physiologically relevant high-content assays for drug discovery
    Matthias Nees and Malin Åkerfelt, University of Turku, Finland
  • GPCR: New frontiers in G protein-coupled receptor drug discovery
    Christopher J. Langmead, Monash Institute of Pharmaceutical Sciences (MIPS) 
  • IN-DEPTH FOCUS: Hit-to-lead
  • APPLICATION NOTE: Direct measurements of cellular metabolism for identification
    of mitochondrial drug targets
    Agilent 
  • IN-DEPTH FOCUS: Targets
  • PROTEOMICS: Proteomics: cracking the molecular mystery of diseases and therapeutics
    Anowarul Amin, National Institutes of Neurological Disorders and Stroke (NINDS), NIH – Bethesda, MD 
  • SUPPLEMENT: Application notes
    With contributions from Eppendorf, IDBS, Intellicyt, Sciex and ThermoFisher Scientific.

 

Issue 4 of Drug Target Review is restricted - login or subscribe free to access

Thank you for visiting our website. To access this content in full you'll need to login. It's completely free to subscribe, and in less than a minute you can continue reading. If you've already subscribed, great - just login.

Why subscribe? Join our growing community of thousands of industry professionals and gain access to:

  • quarterly issues in print and/or digital format
  • case studies, whitepapers, webinars and industry-leading content
  • breaking news and features
  • our extensive online archive of thousands of articles and years of past issues
  • ...And it's all free!

Click here to Subscribe today Login here

 


Send this to a friend