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New Gut Cell Atlas reveals genetic origins of Crohn’s disease
The Gut Cell Atlas comprises 428,000 cells in the gut and sheds light on the origin of Crohn’s disease and other intestinal diseases.
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
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Artificial intelligence could revolutionise glycomics datasets
Researchers have created a tool that allows glycomics datasets to be analysed using artificial intelligence for early cancer diagnoses.
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On-demand webinar: An AI-based approach to phenotypic characterisation of neuronal cells
Evaluation of neurotoxicity effects is an active area of investigation in drug discovery and disease modeling.
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Cartilage growth gene TRPV4 shows promise for joint repair therapy
The discovery that the TRPV4 gene regulates cartilage growth could lead to treatments for osteoarthritis and other cartilage diseases.
whitepaper
Whitepaper: Accelerate antibody screening and characterisation
This whitepaper overviews use of Advanced Flow Cytometry to accelerate antibody screening and characterisation and reveal deeper biological insights.
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Getting “under the skin” of frontotemporal dementia
Researchers at the University of East Finland have been using skin cells to investigate pathological hallmarks in frontotemporal dementia patients.
whitepaper
Whitepaper: Characterising astroglia models
This whitepaper describes several live-cell phenotypic analyses suitable for the characterisation of astroglia cells.
news
New biomarkers may help prevent diabetes-related blindness
US researchers have identified new biomarkers that can detect early changes in the eye that can lead to diabetes-related blindness.
whitepaper
Info kit: Metabolomics in pharmaceutical research
Accelerate the discovery process of new drugs and targets with a better understanding of the metabolome and lipidome during drug development.
whitepaper
Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
news
New research reveals abnormalities in blood vessels of human hearts
A new study has found abnormalities in the blood vessels of human hearts, possibly leading to treatments for cardiac microvascular dysfunction.
whitepaper
Handbook: Latest edition live-cell analysis
The latest edition of the live-cell analysis handbook is a companion guide for live-cell analysis users. Includes discussion of live-cell analysis.
news
Therapeutic target for aggressive cancers discovered through CRISPR
The RNA-modifying protein METTL1 could be targeted to treat some types of aggressive cancers, including brain, blood and kidney.
whitepaper
Whitepaper: Understanding T Cell phenotype and function
This whitepaper overviews the importance of understanding T Cell Biology to build better therapeutics, demonstrates use of advanced flow cytometry.
news
Enzyme found to be an “Achilles’ heel” in ovarian cancers
Scientists have uncovered the crucial role of the enzyme NMNAT-2 in ovarian cancers, as well as other biomarkers that could lead to treatments.
