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Disease Research

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Efficacy of PET imaging in managing chronic liver diseases

8 October 2018 | By Drug Target Review

PET imaging could be used as a non-invasive substitute to painful and complicated liver biopsies for chronic liver disease...

news

Researchers develop a potential tool for efficacious targeted cancer therapy

8 October 2018 | By Drug Target Review

Researchers have developed PeptiENV, a cancer vaccine platform, which can be used to improve the therapeutic efficacy of oncolytic enveloped viruses...

news

Prostate and lung cancers driven by common mechanisms

5 October 2018 | By Iqra Farooq (Drug Target Review)

Lung and prostate small cell carcinomas are driven by common mechanisms, which could lead to the development of one treatment for all small cell cancers...

news

Estradiol exerts anticancer effects in triple-negative breast cancer

5 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer...

news

Nonresponsive NK cells directly impact malaria severity

5 October 2018 | By Drug Target Review

The failure of natural killer cells (NK cells) to respond to infection explains why malaria causes a worse reaction in some patients than others.

news

RNA-seq of 20,000 cardiac cells reveals heart disease insights

5 October 2018 | By Iqra Farooq (Drug Target Review)

RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...

article

Exploring quality of life for stoma patients

4 October 2018 | By Drug Target Review

There are many people with a stoma living in the community in the UK. A commonly reported problem with living with a stoma is a poor quality of life because of uncertainty and doubts in the mind of the person with a stoma. The focus of this article is reviewing…

news

Chemotherapy and APOE4 linked to cognitive issues

4 October 2018 | By Iqra Farooq (Drug Target Review)

Both human and mouse models show that chemotherapy and APOE4 are linked to cognitive issues faced by patients who overcome cancer...

news

Nuclear tracer helps to study the aging brain

4 October 2018 | By Drug Target Review

A PET nuclear tracer could help researchers to understand neurodegeneration in aging brains better, as it enters the brain and distributes quickly...

news

SERDs molecules could spur a new class of drugs for breast cancer

4 October 2018 | By Drug Target Review

Stevens researchers design and develop a new class of molecules for breast cancer therapy...

news

Umbilical cord stem cells used for early repair of cleft palate

3 October 2018 | By Drug Target Review

Stem cells harvested from the umbilical cord after birth could lead to a therapy to treat cleft lip and palate without the traditional surgery...

news

Alpaca immune system reveals a potential treatment for cancer

3 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...

news

Cancer immunotherapy researchers win Nobel prize

3 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...

news

Rare mechanism for ALL to relapse after CAR-T therapy

2 October 2018 | By Iqra Farooq (Drug Target Review)

A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...

news

Targets for chronic kidney disease treatment

2 October 2018 | By Iqra Farooq (Drug Target Review)

The DAB2 pathway could be a crucial target in treating CKD, as mouse models show a decrease in DAB2 leads to prevention of the condition...

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