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Drug target identified in oestrogen receptors
A bridge-like structure in oestrogen has been identified by researchers at Case Western Reserve University School of Medicine as a potential drug target...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Rutin could be effective in treating snakebites from pit vipers
The action of a venomous snakebite from vipers could be treated using a flavonoid called rutin, an inexpensive plant based compound...
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Vaccine offers complete protection against Ebola virus
Researchers at The Wistar Institute have developed a DNA based vaccine that has offered compete protection against the Ebola virus in preclinical trials...
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Immunotherapy could cure advanced pancreatic cancer
Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...
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Early treatment could reverse autistic behaviour in tuberous sclerosis
Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
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Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
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Elrig 2018: Drug discovery using small and large molecules
The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...
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Biodegradable devices speed up nerve regeneration
Researchers have developed an implantable and biodegradable device to aid the regeneration of nerve after damage from accidents and sports injuries...
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Prostate and lung cancers driven by common mechanisms
Lung and prostate small cell carcinomas are driven by common mechanisms, which could lead to the development of one treatment for all small cell cancers...
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RNA-seq of 20,000 cardiac cells reveals heart disease insights
RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...
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Cancer immunotherapy researchers win Nobel prize
Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...
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Rare mechanism for ALL to relapse after CAR-T therapy
A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...
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Targets for chronic kidney disease treatment
The DAB2 pathway could be a crucial target in treating CKD, as mouse models show a decrease in DAB2 leads to prevention of the condition...
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Amazonian plant provides anti-tumour activity
A plant from the Amazonian region of Colombia has shown anti-tumour properties against human liver cancer cells, but not against healthy cells...
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KCNB1 may be a root cause of Alzheimer’s disease
Researchers have identified that levels of the protein KCNB1 are increased in Alzheimer's brains, which may cause the increase of amyloid-beta plaques...
