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Drug Target Review – Issue 2 2023
A new Drug Target Review issue is now ready to download! This issue features articles on cell and gene therapy, imaging and screening.
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Imaging
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New detection system for viral infections helps vaccine and drug development
Out of the US, a newly developed a rapid, stain-free, and automated viral plaque detection system enabled by holography and deep learning, is a cost-effective way of observing the formation of viral plaques caused by viral infections over a layer of cells.
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DNA technology helps slow down and scan molecules multiple times
Swiss researchers have achieved near-perfect control over the manipulation of individual DNA molecules, allowing them to be identified and characterised with unprecedented precision
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AI-based technology offers accurate analysis of cardiac disease
A study out of South Korea outlines the potential of an AI-based imaging tool for diagnosing and analysing cardiac disease.
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Novel imaging technique captures COVID-19’s impact on the brain
A form of MRI is a better alternative to many existing imaging technologies when looking at how COVID-19 can change the human brain.
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Predicting cerebrovascular diseases with retinal imaging
New imaging approach reveals that changes in retinal microcirculation may indicate cerebrovascular diseases that involve reduced blood flow.
webinar
Innovations in organoid modelling for disease modelling and cell therapy
14 June 2023 | By Sartorius
Watch our virtual panel, where you'll uncover the game-changing advantages of organoids over traditional 2D cultures. Our experts will explore the immense potential of organoids in oncology and immuno-oncology research.
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Novel mutation linked to late-onset Alzheimer’s disease
Chinese researchers discover a mutation, referred to as the "Shanghai APP" mutation, which has been linked to late-onset Alzheimer's disease and offers fresh insights into the disease's underlying molecular mechanisms.
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Amino Acid PET effective in distinguishing brain metastases from treatment-related changes
US study uncovers the best way to treat recurrent or progressive brain metastases using an amino acid PET technique.
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Examining brain’s glymphatic system may shed light on brain diseases
US researchers used focused ultrasound with microbubbles to examine glymphatic system of the brain, which plays a crucial role in clearing metabolic waste from the brain.
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Linking air pollution and lung disease
USC researchers gain valuable insights into the biological processes underlying the association between air pollution and lung disease. By unravelling the mechanisms involved, researchers are hopeful that new strategies can be developed to mitigate the adverse effects of pollution exposure and improve the prevention and treatment of related diseases.
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New technique enables in vivo analysis of protein complexes
Chinese researchers use a glycosidic-bond-based mass-spectrometry-cleavable cross-linker to analyse proteins in vivo.
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Study links nutrients, brain structure, cognition in healthy aging
US researchers found that nutrient intake, brain structure and cognitive function contribute to healthier brains in aging adults, by looking at correlating blood markers.
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Rhythmic brain activity helps maintain temporary memories
US researchers have discovered that rhythmic brain activity organises the neuronal pathways that maintain short-term memories.
