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Podcast: Challenges for the bioanalysis of CAR-T Cells
Podcast discussion featuring CAR-T Cell therapy development and reviewing current challenges and future potentials for these cell therapies.
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Immunology
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Ultrasound-guided microbubbles boost immunotherapy efficacy
Researchers have developed an immunotherapy platform to improve both antitumor immune responses and responses to checkpoint inhibitors
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Preclinical study highlights an effective combination immunotherapy for liver cancer
Study in mice significantly slowed liver tumour growth and activated anti-tumour immune response, highlighting an effective immunotherapy for liver cancer.
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Bulletin: Cancer vaccines: getting ready for a decade of big breakthroughs and novel treatments
Hear from leading industry experts in this emerging field who discuss: challenges related to antigen and adjuvant selection, vaccine design, immune response improvement and future treatment options.
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Whitepaper: Recombinant protein expression using a BEVS
In this article, Sino Biological highlight the importance of recombinant protein expression using a baculovirus-insect cell system (BEVS) and application of BEVS.
webinar
Assays for protein degradation therapeutics to accelerate undruggable proteome discoveries
9 May 2022 | By PerkinElmer and C4
Looking for a way to address the undruggable proteins in the human body? Watch this free on-demand webinar where industry experts discuss strategies to accelerate TPD drug discovery efforts using high-throughput cell-based assays.
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Infographic: Overview of the CAR-T cell therapy workflow
Find out more about the CAR-T cell therapy workflow in this informative infographic from Bio-Rad Laboratories (CA, USA). Discover some of the challenges associated with CAR-T cell R&D as well as technologies and reagents used for bioanalytical analysis.
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Video: Anti-Idiotypic antibodies for development of CAR T cell therapies
Interview with Michael Schwenkert, Bio-Rad Laboratories, on best practices for the characterisation and quality control of anti-idiotypic antibodies for bioanalysis.
news
Biodegradable gel boosts immune system’s attack on several cancers in mice
A new biodegradable gel can release drugs and special antibodies that simultaneously deplete macrophages from the surgical site and activate T cells.
article
Viewing disease through the lens of memory B cells: improving cancer and infectious disease treatment
Looking at disease through a patient’s memory B cells can reveal vulnerabilities within pathogens. In this article, Dr Purnanand Sarma, President and Chief Executive Officer of Immunome, explores how advancements in memory B-cell antibody-based treatments will improve our understanding of how these cells can aid in fighting cancer and other diseases.
whitepaper
Bulletin: Utilising the multiparameter capability of the Ze5 Cell Analyser to monitor T cell exhaustion and effects of immunotherapy
Read this bulletin to learn about a Bio-Rad study where they developed and tested a 16-parameter flow cytometry panel applicable to the interrogation of a range of biologically relevant markers of T cell activation.
news
Two-faced protein both inhibits and activates B cell receptor signalling
New research could point towards a way to restore immune function in patients with immune disorders involving B cell signalling deficiencies.
news
Potential origins of scleroderma highlighted in new study
Researchers at the Weizmann Institute of Science have shown that fibroblasts may be a factor in the origin of scleroderma.
news
Study highlights the essential role of dendritic cells in immunotherapy
Researchers have discovered how immune system dendritic cells are key to maintaining and regulating response to immunotherapy.
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Novel systems for realising the promise of DNA vaccines and enabling the next generation of genetic medicines
Dr John Lewis, CEO of Entos Pharmaceuticals, outlines how an innovative proteolipid platform could enable a new class of DNA-based vaccines in this article.
